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The 1845 Grand Liverpool Steeplechase was the seventh annual running of a Handicap Steeple-chase, later to become known as the Grand National Steeplechase, a horse race which took place at Aintree Racecourse near Liverpool on Wednesday 5 March 1845 and attracted a field of 15 runners. It was won by the unconsidered outsider Cure-All, ridden by William Loft in a record time of 10 minutes, 47 seconds.