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(R)-p-Isothiocyanatobenzoylecgonine methyl ester (p-ISOCOC) is a cocaine analogue and irreversible (covalent) binding inhibitor of the cocaine receptor, as well as irreversible blocker of dopamine uptake by DAT (the latter being unlike its C3 homologue ). p-Isococ also blocks the high-affinity cocaine site in preference to the low-affinity site.

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dbo:abstract
  • (R)-p-Isothiocyanatobenzoylecgonine methyl ester (p-ISOCOC) is a cocaine analogue and irreversible (covalent) binding inhibitor of the cocaine receptor, as well as irreversible blocker of dopamine uptake by DAT (the latter being unlike its C3 homologue ). p-Isococ also blocks the high-affinity cocaine site in preference to the low-affinity site. (en)
dbo:alternativeName
  • p-ISOCOC, p-Isococ (en)
dbo:iupacName
  • Methyl (1R,2R,3S,5S)-3-[(4-isothiocyanatobenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate (en)
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  • 33739864 (xsd:integer)
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  • 2843 (xsd:nonNegativeInteger)
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  • 1017691406 (xsd:integer)
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  • P-ISOCOC.svg (en)
dbp:name
  • -p-Isothiocyanatobenzoylecgonine methyl ester (en)
dbp:othernames
  • p-ISOCOC, p-Isococ (en)
dbp:pin
  • Methyl -3-[oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate (en)
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  • 460960121 (xsd:integer)
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  • (R)-p-Isothiocyanatobenzoylecgonine methyl ester (p-ISOCOC) is a cocaine analogue and irreversible (covalent) binding inhibitor of the cocaine receptor, as well as irreversible blocker of dopamine uptake by DAT (the latter being unlike its C3 homologue ). p-Isococ also blocks the high-affinity cocaine site in preference to the low-affinity site. (en)
rdfs:label
  • (R)-p-Isothiocyanatobenzoylecgonine methyl ester (en)
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foaf:name
  • (R)-p-Isothiocyanatobenzoylecgonine methyl ester (en)
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