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Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures in people with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD). Ganaxolone was approved for medical use in the United States in March 2022.

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  • Ganaxolon (de)
  • Ganaxolone (en)
  • Ganaxolone (it)
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  • Ganaxolon ist ein Arzneistoff aus der Gruppe der neuroaktiven Steroide. Unter dem Namen Ztalmy (Hersteller: ) wurde er im März 2022 in den USA zugelassen zur oralen Behandlung von Krampfanfällen im Zusammenhang mit einem bei Patienten ab 2 Jahren. Dabei handelt es sich um eine sehr selten auftretende Erbkrankheit, die zu häufigen Krampfanfällen kurz nach der Geburt führt und eine schwere Beeinträchtigung der neurologischen Entwicklung zur Folge hat. (de)
  • Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures in people with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD). Ganaxolone was approved for medical use in the United States in March 2022. (en)
  • Il ganaxolone (INN, anche noto come CCD-1042) è un farmaco steroideo correlato all'allopregnanolone avente effetti sedativo, ansiolitico e anticonvulsivo.È un modulatore allosterico positivo potente e selettivo del recettore GABAA.Il ganaxolone protegge dalle crisi convulsive in diversi modelli animali, inclusi i modelli di innesco "a 6 Hz" e dell'amigdalaA differenza delle benzodiazepine, non c'è alcuna tolleranza negli effetti anticonvulsivi del ganaxolone. (it)
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