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Copenhagen disease, sometimes known as Copenhagen syndrome or progressive non-infectious anterior vertebral fusion (PAVF), is a unique spinal disorder with distinctive radiological features. This is a rare childhood disease of unknown cause, affecting females slightly more than males (60%). Prevalence is unknown, but there have been approximately 80–100 individuals with Copenhagen disease reported since 1949. However, there is still little known research due to the rarity of the disease. The disease is so rare that the National Organization for Rare Diseases does not even mention Copenhagen disease in their database.

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  • Copenhagen disease (en)
rdfs:comment
  • Copenhagen disease, sometimes known as Copenhagen syndrome or progressive non-infectious anterior vertebral fusion (PAVF), is a unique spinal disorder with distinctive radiological features. This is a rare childhood disease of unknown cause, affecting females slightly more than males (60%). Prevalence is unknown, but there have been approximately 80–100 individuals with Copenhagen disease reported since 1949. However, there is still little known research due to the rarity of the disease. The disease is so rare that the National Organization for Rare Diseases does not even mention Copenhagen disease in their database. (en)
foaf:name
  • Copenhagen disease (en)
name
  • Copenhagen disease (en)
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diagnosis
ICD
  • Q87.8 (en)
Orphanet
causes
  • Unknown (en)
field
  • Orthopedic (en)
synonyms
  • Progressive non-infectious anterior vertebral fusion, Copenhagen syndrome (en)
has abstract
  • Copenhagen disease, sometimes known as Copenhagen syndrome or progressive non-infectious anterior vertebral fusion (PAVF), is a unique spinal disorder with distinctive radiological features. This is a rare childhood disease of unknown cause, affecting females slightly more than males (60%). Prevalence is unknown, but there have been approximately 80–100 individuals with Copenhagen disease reported since 1949. However, there is still little known research due to the rarity of the disease. The disease is so rare that the National Organization for Rare Diseases does not even mention Copenhagen disease in their database. Copenhagen disease affects the lower back, as can be seen on MRI scans. It is characterized by the progressive fusion of the anterior vertebral body in the thoracolumbar region of the spine. (en)
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ICD10
  • Q87.8
ORPHA
  • 2062
medical diagnosis
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