Conjugated fatty acids is jargon for polyunsaturated fatty acids containing at least one pair of conjugated double bonds. An example of a conjugated fatty acid is the rumenic acid, found in the meat and milk of ruminants. Most unsaturated fatty acids that are doubly unsaturated do not feature conjugation, e.g., linoleic acid and linoelaidic acid. Conjugated fatty acids can have either a cis or trans configuration. For instance, the rumenic acid (cis9, trans11) is a conjugated trans fatty acid.
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| - Àcid gras conjugat (ca)
- Conjugated fatty acid (en)
- Acidi grassi coniugati (it)
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| - Els àcids grassos conjugats són àcids grassos poliinsaturats en els quals, com a mínim, un parell de dobles enllaços estan separats per només un enllaç simple, i no estan interromputs per metilè. Un exemple és l'àcid linoleic conjugat: Els àcids grassos conjugats (les sigles en anglès són:CFAs) són una mescla d'isòmers, de posició i de geometria, amb dobles enllaços conjugats. La conjugació dona lloc a la deslocalització electrònica dels electrons al llarg del sistema. (ca)
- Conjugated fatty acids is jargon for polyunsaturated fatty acids containing at least one pair of conjugated double bonds. An example of a conjugated fatty acid is the rumenic acid, found in the meat and milk of ruminants. Most unsaturated fatty acids that are doubly unsaturated do not feature conjugation, e.g., linoleic acid and linoelaidic acid. Conjugated fatty acids can have either a cis or trans configuration. For instance, the rumenic acid (cis9, trans11) is a conjugated trans fatty acid. (en)
- Un acido grasso coniugato è un acido grasso polinsaturo contenente due o più doppi legami alternati ad un legame singolo, con sequenza C=C‒C=C, al contrario dei più comuni acidi grassi polinsaturi non coniugati che hanno un gruppo metilene tra i 2 doppi legami, C=C‒C‒C=C .I legami coniugati comportano una delocalizzazione degli elettroni.Gli acidi grassi coniugati sono particolarmente suscettibili all'ossidazione e gli oli ad alto tenore di acidi grassi coniugati trienoici o tetraenoici sono oli siccativi che polimerizzano esposti all'aria ed al calore in tempi molto più brevi dell'olio di lino. Gli oli vegetali ricchi di acidi grassi coniugati, come l'olio di tung (Aleurites fordii), sono relativamente rari, e per una loro produzione a costi più bassi sono state sviluppate varietà transge (it)
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| - Els àcids grassos conjugats són àcids grassos poliinsaturats en els quals, com a mínim, un parell de dobles enllaços estan separats per només un enllaç simple, i no estan interromputs per metilè. Un exemple és l'àcid linoleic conjugat: Els àcids grassos conjugats (les sigles en anglès són:CFAs) són una mescla d'isòmers, de posició i de geometria, amb dobles enllaços conjugats. La conjugació dona lloc a la deslocalització electrònica dels electrons al llarg del sistema. (ca)
- Conjugated fatty acids is jargon for polyunsaturated fatty acids containing at least one pair of conjugated double bonds. An example of a conjugated fatty acid is the rumenic acid, found in the meat and milk of ruminants. Most unsaturated fatty acids that are doubly unsaturated do not feature conjugation, e.g., linoleic acid and linoelaidic acid. Some conjugated fatty acids may confer health benefits ranging from the prevention of hypertension to protection against certain forms of cancer, although more research is needed to confirm such effects. Clinical studies and animal models have shown that conjugated fatty acids confer physiological benefits such as the regulation of the synthesis and breakdown of lipids, reduction of inflammation, and antioxidant properties. Conjugated fatty acids include isomers of linoleic acid. Conjugated analogues linoleic acids are the most investigated conjugated fatty acids. The reason why the isomer of conjugated fatty acids are studied is because they have the potential to treat human illnesses. A biological activity that conjugated fatty acids have been studied for is the reduction of body fat and the increasing of lean body mass. There are experimental models that proved the ability of conjugated linoleic acid to reduce fat levels. This is why the scientific community see the potential to use conjugated fatty acids with active treatments to prevent obesity. However, research studies made in humans are in disagreement even though these studies have proven that the supplementation of conjugated linoleic acid has some benefits such as weight loss. On top of the research on conjugated linoleic acid on body weight regulation, isomers of conjugated linoleic acid have been shown, in-vitro, to inhibit the growth and division of a cell to two daughter cells, initiate cell death, and interfere with mutagenicity in human tumor cells. Conjugated fatty acids can have either a cis or trans configuration. For instance, the rumenic acid (cis9, trans11) is a conjugated trans fatty acid. Studies have suggested that conjugated linoleic acids, an isomer of conjugated fatty acids, can modulate inflammatory responses in the body. However, CLA’s anti-inflammatory properties correlate to isomer dependence. For instance, (cis-9, trans-11) CLA has been shown to have a decreased inflammatory effect on adipose tissues of mice with obesity-causing genes, while (trans-10, cis-12) CLA reduces obesity in mice without affecting insulin resistance or adipose tissue inflammation. (en)
- Un acido grasso coniugato è un acido grasso polinsaturo contenente due o più doppi legami alternati ad un legame singolo, con sequenza C=C‒C=C, al contrario dei più comuni acidi grassi polinsaturi non coniugati che hanno un gruppo metilene tra i 2 doppi legami, C=C‒C‒C=C .I legami coniugati comportano una delocalizzazione degli elettroni.Gli acidi grassi coniugati sono particolarmente suscettibili all'ossidazione e gli oli ad alto tenore di acidi grassi coniugati trienoici o tetraenoici sono oli siccativi che polimerizzano esposti all'aria ed al calore in tempi molto più brevi dell'olio di lino. Gli oli vegetali ricchi di acidi grassi coniugati, come l'olio di tung (Aleurites fordii), sono relativamente rari, e per una loro produzione a costi più bassi sono state sviluppate varietà transgeniche. Il processo di isomerizzazione degli acidi grassi polinsaturi che può trasformare dieni o trieni non coniugati in coniugati, può essere realizzato semplicemente riscaldando ad alte temperature un olio vegetale per tempi relativamente lunghi, temperature e tempi che normalmente si evita di utilizzare nella tipica raffinazione degli oli, proprio per impedirne la polimerizzazione. (it)
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