The 2021–22 Southern Utah Thunderbirds men's basketball team represented Southern Utah University in the 2021–22 NCAA Division I men's basketball season. The Thunderbirds, led by sixth-year head coach Todd Simon, played their home games at the America First Event Center in Cedar City, Utah as members of the Big Sky Conference. They finished the season 23–12, 14–6 in Big Sky play to finish in second place. They lost in the quarterfinals of the Big Sky tournament to Portland State. They received an invitation to The Basketball Classic tournament where they defeated Kent State, UTEP, and Portland to advance to the tournament semifinals. There they lost to Fresno State.