Pantelimon I. Sinadino was a Bessarabian politician of Greek descent. He served as mayor of Chișinău in 1837–1839 and 1840–1842, being preceded and succeeded by Dimitrie Lovcinski. Sinadino was the grandfather of Pantelimon V. Sinadino, who also was mayor of Chișinău between 1903–1904, 1905–1907 and 1909–1910.