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About: L1 family     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : dbo:Protein, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculeBiomoleculeProteinprotein New Facet based on Instances of this Class

The L1 family is a family of cell adhesion molecules that includes four different L1-like proteins. They are members of the immunoglobulin superfamily (IgSF CAM). The members of the L1-family in humans are called L1 or L1cam, CHL1 (close homologue of L1), Neurofascin and NRCAM (NgCAM related cell adhesion molecule). L1 family members are found on neurons, especially on their axons. Sometimes they are found on glia, such as Schwann cells, radial glia and Bergmann glia cells and, as such, are important for neural cell migration during development. L1 family members are expressed throughout the vertebrate and invertebrate kingdoms.