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Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism.

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  • Diphenylpyralin (de)
  • Diphenylpyraline (en)
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  • Diphenylpyralin ist ein Arzneistoff, der als systemisches Antiallergikum Anwendung findet. Er gehört zur Wirkstoffklasse der Antihistaminika der ersten Generation bzw. zur Stoffgruppe der . Diphenylpyralin war in Deutschland (als Grippemittel) und der Schweiz (als perorales Schnupfenmittel) in Form von Kombinationspräparaten im Handel. Außer der antiallergischen Wirkung wird dem Arzneistoff auch eine sekretionshemmende Wirkung zugeschrieben. (de)
  • Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism. (en)
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  • AA07 (en)
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  • R06 (en)
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  • DB01146 (en)
elimination half-life
H
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KEGG
  • D07862 (en)
legal status
  • Rx-only (en)
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