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Statements

Subject Item
dbr:7alpha-hydroxysteroid_dehydrogenase
rdf:type
yago:Unit109465459 yago:Molecule114682133 yago:Matter100020827 yago:Abstraction100002137 yago:Catalyst114723628 yago:Macromolecule114944888 dbo:Biomolecule yago:WikicatEnzymesOfKnownStructure yago:Enzyme114732946 yago:OrganicCompound114727670 yago:Chemical114806838 yago:Relation100031921 yago:Compound114818238 yago:Protein114728724 owl:Thing yago:Material114580897 wikidata:Q206229 dbo:Enzyme yago:PhysicalEntity100001930 wikidata:Q8047 yago:Part113809207 yago:Thing100002452 yago:WikicatNADH-dependentEnzymes yago:Activator114723079 yago:Substance100019613
rdfs:label
7alpha-hydroxysteroid dehydrogenase 7alfa-idrossisteroide deidrogenasi 7α-ヒドロキシステロイドデヒドロゲナーゼ
rdfs:comment
In enzymology, a 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) is an enzyme that catalyzes the chemical reaction 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + NAD+ 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. 7α-ヒドロキシステロイドデヒドロゲナーゼ（7α-hydroxysteroid dehydrogenase）は、次の化学反応を触媒する酸化還元酵素である。 3α,7α,12α-トリヒドロキシ-5β-コラン酸 + NAD+ 3α,12α-ジヒドロキシ-7-オキソ-5β-コラン酸 + NADH + H+ 反応式の通り、この酵素の基質はとNAD+、生成物はとNADHとH+である。 組織名は7α-hydroxysteroid:NAD+ 7-oxidoreductaseで、別名に7α-HSDHがある。 La 7alfa-idrossisteroide deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 3α,7α,12α-triidrossi-5β-ciolanato + NAD+ ⇄ 3β,12α-diidrossi-7-osso-5β-ciolanato + NADH + H+ L'enzima catalizza l'ossidazione del gruppo 7α-idrossile degli acidi biliari e degli alcoli sia nella forma libera che legata. Gli enzimi di Bacteroides fragilis e Clostridium possono utilizzare anche il NADP+.
foaf:name
7-alpha-hydroxysteroid dehydrogenase
dbp:name
7
dcterms:subject
dbc:Enzymes_of_known_structure dbc:EC_1.1.1 dbc:NADH-dependent_enzymes
dbo:wikiPageID
13902875
dbo:wikiPageRevisionID
958662651
dbo:wikiPageWikiLink
dbr:Catalysis dbr:Hydrogen_ion dbr:Tertiary_structure dbc:EC_1.1.1 dbr:Substrate_(biochemistry) dbr:Enzyme dbr:List_of_enzymes dbr:3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate dbr:Chemical_reaction dbr:3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate dbc:NADH-dependent_enzymes dbr:Nicotinamide_adenine_dinucleotide dbr:Oxidoreductase dbr:Product_(chemistry) dbr:Protein_Data_Bank dbr:Enzymology dbc:Enzymes_of_known_structure
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dbp:casNumber
39361
dbp:ecNumber
1.1
dbp:goCode
8709
dbp:iubmbEcNumber
1
dbo:abstract
7α-ヒドロキシステロイドデヒドロゲナーゼ（7α-hydroxysteroid dehydrogenase）は、次の化学反応を触媒する酸化還元酵素である。 3α,7α,12α-トリヒドロキシ-5β-コラン酸 + NAD+ 3α,12α-ジヒドロキシ-7-オキソ-5β-コラン酸 + NADH + H+ 反応式の通り、この酵素の基質はとNAD+、生成物はとNADHとH+である。 組織名は7α-hydroxysteroid:NAD+ 7-oxidoreductaseで、別名に7α-HSDHがある。 In enzymology, a 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) is an enzyme that catalyzes the chemical reaction 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + NAD+ 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase. Other names in common use include 7alpha-hydroxy steroid dehydrogenase, and 7alpha-HSDH. La 7alfa-idrossisteroide deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 3α,7α,12α-triidrossi-5β-ciolanato + NAD+ ⇄ 3β,12α-diidrossi-7-osso-5β-ciolanato + NADH + H+ L'enzima catalizza l'ossidazione del gruppo 7α-idrossile degli acidi biliari e degli alcoli sia nella forma libera che legata. Gli enzimi di Bacteroides fragilis e Clostridium possono utilizzare anche il NADP+.
prov:wasDerivedFrom
wikipedia-en:7alpha-hydroxysteroid_dehydrogenase?oldid=958662651&ns=0
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3103
dbo:ecNumber
1.1.1.159
foaf:isPrimaryTopicOf
wikipedia-en:7alpha-hydroxysteroid_dehydrogenase