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<http://dbpedia.org/resource/Hofmeister_series>	<http://purl.org/dc/terms/subject>	<http://dbpedia.org/resource/Category:Laboratory_techniques> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://rdf.freebase.com/ns/m.03bxhq1> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://purl.org/dc/terms/subject>	<http://dbpedia.org/resource/Category:Solutions> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Technique105665146> .
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<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Physical_chemistry> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Ionicity> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"Die Hofmeister-Reihe (auch Hofmeister-Serie oder Lyotrope Serie) beschreibt die unterschiedlichen F\u00E4llungswirkungen von Salzen. Der Chemiker Franz Hofmeister untersuchte 1888 die proteinf\u00E4llende Wirkung von Salzen und damit der in Wasser gel\u00F6sten Ionen. Er fand dabei empirisch Ionen-Sequenzen, die die St\u00E4rke des Einflusses auf die in Wasser gel\u00F6sten Biomolek\u00FCle charakterisiert."@de .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Salting_out> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Lyotropy> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Laboratory_techniques> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Cite_book> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Salting_in> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://nl.dbpedia.org/resource/Hofmeister-reeks> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/thumbnail>	<http://commons.wikimedia.org/wiki/Special:FilePath/Prag_Medizinische_Fakult\u00E4t_Franz_Hofmeister_448.jpg?width=300> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://purl.org/dc/terms/subject>	<http://dbpedia.org/resource/Category:Physical_chemistry> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Ammonium_sulfate_precipitation> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u041B\u0456\u043E\u0442\u0440\u043E\u043F\u043D\u0438\u0439 \u0440\u044F\u0434 (\u0440\u043E\u0441. \u043B\u0438\u043E\u0442p\u043E\u043F\u043D\u044B\u0439 p\u044F\u0434, [\u0440\u044F\u0434 \u0413\u043E\u0444\u043C\u0435\u0439\u0441\u0442\u0435\u0440\u0430], \u0430\u043D\u0433\u043B. lyotropic [Hofmeister] serie) \u2014 \u0440\u044F\u0434 \u0456\u043E\u043Di\u0432, \u0449\u043E \u0440\u043E\u0437\u0442\u0430\u0448\u043E\u0432\u0430\u043Di \u0432 \u043F\u043E\u0440\u044F\u0434\u043A\u0443 \u043Fi\u0434\u0441\u0438\u043B\u0435\u043D\u043D\u044F \u0447\u0438 \u043F\u043E\u0441\u043B\u0430\u0431\u043B\u0435\u043D\u043D\u044F \u0457\u0445\u043D\u044C\u043E\u0433\u043E \u0432\u043F\u043B\u0438\u0432\u0443 \u043D\u0430 \u0432\u043B\u0430\u0441\u0442\u0438\u0432\u043E\u0441\u0442i \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0438\u043A\u0430 (\u0432'\u044F\u0437\u043A\u0456\u0441\u0442\u044C, \u043F\u043E\u0432\u0435\u0440\u0445\u043D\u0435\u0432\u0438\u0439 \u043D\u0430\u0442\u044F\u0433, \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0456\u0441\u0442\u044C i \u0442. \u043F.), \u0430 \u0442\u0430\u043A\u043E\u0436 \u043D\u0430 \u0448\u0432\u0438\u0434\u043Ai\u0441\u0442\u044C \u0440\u0435\u0430\u043A\u0446i\u0439 \u0443 \u0434\u0430\u043D\u043E\u043C\u0443 \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0438\u043A\u043E\u0432i \u0442\u0430 i\u043D\u0448i \u0444i\u0437\u0438\u043A\u043E-\u0445\u0456\u043Ci\u0447\u043Di \u043F\u0440\u043E\u0446\u0435\u0441\u0438. \u0421\u0438\u043D\u043E\u043D\u0456\u043C \u2014 \u0440\u044F\u0434 \u0413\u043E\u0444\u043C\u0435\u0439\u0441\u0442\u0435\u0440\u0430."@uk .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Ionic_strength> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/ns/prov#wasDerivedFrom>	<http://en.wikipedia.org/wiki/Hofmeister_series?oldid=1107245658&ns=0> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"The Hofmeister series or lyotropic series is a classification of ions in order of their lyotrophic properties, which is the ability to salt out or salt in proteins. The effects of these changes were first worked out by Franz Hofmeister, who studied the effects of cations and anions on the solubility of proteins. Hofmeister discovered a series of salts that have consistent effects on the solubility of proteins and (it was discovered later) on the stability of their secondary and tertiary structure. Anions appear to have a larger effect than cations, and are usually ordered"@en .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Ribonuclease_A> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Part113809207> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Solubility> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"La Serie de Hofmeister o Serie Liotr\u00F3pica es una clasificaci\u00F3n de los iones en orden de su capacidad para generar precipitaci\u00F3n salina en las prote\u00EDnas.\u200B Los efectos de estos cambios fueron trabajados por primera vez por Franz Hofmeister, quien estudi\u00F3 los efectos de los cationes y aniones en la solubilidad de las prote\u00EDnas\u200B Hofmeister descubri\u00F3 una serie de sales que tienen efectos consistentes en la solubilidad de las prote\u00EDnas y (se descubri\u00F3 m\u00E1s tarde) en la estabilidad de su estructura secundaria y terciaria. Los aniones parecen tener un efecto mayor que los cationes,\u200B y normalmente se ordenan (Esto es un listado parcial ; muchos m\u00E1s las sales han sido estudiadas.)El orden de los cationes podr\u00EDa ser: El mecanismo de la serie de Hofmeister no est\u00E1 del todo claro, pero no parece ser el resultado de los cambios en la estructura general del agua, sino que pueden ser m\u00E1s importantes las interacciones m\u00E1s espec\u00EDficas entre los iones y las prote\u00EDnas y los iones y las mol\u00E9culas de agua que est\u00E1n en contacto directo con las prote\u00EDnas.\u200B Estudios recientes de simulaci\u00F3n han demostrado que la variaci\u00F3n de la energ\u00EDa de disoluci\u00F3n entre los iones y las mol\u00E9culas de agua circundantes subyace al mecanismo de la serie de Hofmeister.\u200B\u200B Los primeros miembros de la serie aumentan la tensi\u00F3n superficial del disolvente y disminuyen la solubilidad de las mol\u00E9culas no polares (\"salting out\"); as\u00ED, refuerzan la interacci\u00F3n hidrof\u00F3bica. En cambio, las sales posteriores de la serie aumentan la solubilidad de las mol\u00E9culas no polares (\"salting in\") y disminuyen el orden en el agua; as\u00ED, debilitan el efecto hidrof\u00F3bico.\u200B El salting out se aprovecha com\u00FAnmente en la purificaci\u00F3n de las prote\u00EDnas mediante el uso de sulfato de amonio. Sin embargo, estas sales tambi\u00E9n interact\u00FAan directamente con las prote\u00EDnas (que est\u00E1n cargadas y tienen fuertes momentos dipolares) e incluso pueden unirse espec\u00EDficamente (por ejemplo, el fosfato y el sulfato se unen a la ribonucleasa A). Los iones que tienen un fuerte efecto de \"salaz\u00F3n\" como el I- y el SCN- son desnaturalizantes fuertes, porque salan en el grupo de los p\u00E9ptidos, y por lo tanto interact\u00FAan mucho m\u00E1s fuertemente con la forma desplegada de una prote\u00EDna que con su forma nativa. En consecuencia, cambian el equilibrio qu\u00EDmico de la reacci\u00F3n de plegamiento hacia la prote\u00EDna desdoblada. \u200B La desnaturalizaci\u00F3n de las prote\u00EDnas mediante una soluci\u00F3n acuosa que contiene muchos tipos de iones es m\u00E1s complicada, ya que todos los iones pueden actuar, seg\u00FAn su actividad de Hofmeister, (un n\u00FAmero fraccionario que especifica la posici\u00F3n del ion en la serie) en t\u00E9rminos de su eficiencia relativa en la desnaturalizaci\u00F3n de una prote\u00EDna de referencia. El concepto de ionicidad de Hofmeister (Ih) ha sido invocado por Dharma-wardana et. al.\u200B donde se propone definir la Ih como una suma, sobre todas las especies i\u00F3nicas, del producto de la concentraci\u00F3n i\u00F3nica (fracci\u00F3n molar) y un n\u00FAmero fraccionario que especifica la \"fuerza Hofmeister\" del ion en la desnaturalizaci\u00F3n de una determinada prote\u00EDna de referencia. El concepto de ionicidad (como medida de la fuerza de Hofmeister) que se utiliza aqu\u00ED debe distinguirse de la fuerza i\u00F3nica tal como se utiliza en la electroqu\u00EDmica, y tambi\u00E9n de su uso en la teor\u00EDa de los semiconductores s\u00F3lidos\u200B"@es .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"Hofmeister series"@en .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Compound114818238> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageID>	"5265621"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Method105660268> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Secondary_structure> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"De Hofmeister-reeks of lyotropische reeks is een classificatie van ionen op volgorde van hun vermogen om de structuur van water aan te passen. De effecten van deze veranderingen zijn voor het eerst uitgewerkt door , die de effecten van kationen en anionen op de oplosbaarheid van eiwitten bestudeerde. Hofmeister ontdekte een reeks van zouten die consistente effecten hebben op de oplosbaarheid van eiwitten en (zo werd later ontdekt) op de stabiliteit van hun secundaire en tertiaire structuur. Anionen lijken een groter effect te hebben dan kationen en worden gewoonlijk als volgt gesorteerd: Dit is echter een gedeeltelijke lijst: er zijn veel meer zouten onderzocht. De volgorde van kationen wordt gewoonlijk als volgt gegeven: Het mechanisme van de Hofmeister-reeks is niet volledig duidelijk maar lijkt niet te stammen uit veranderingen in de algemene waterstructuur, maar eerder uit specifieke interacties tussen ionen en eiwitten en ionen en de watermoleculen die direct contact hebben met de eiwitten. Vroege leden van de reeks verhogen de oppervlaktespanning van water en verminderen de oplosbaarheid van apolaire moleculen (uitzouten); ze versterken de . Late zouten in de reeks verhogen de oplosbaarheid van apolaire moleculen (inzouten) en verhogen de orde in water; ze verzwakken het . Het uitzout-effect wordt veelal gebruikt in eiwitzuivering door middel van . Echter, deze zouten hebben ook een directe interactie met eiwitten (welke geladen zijn en sterke dipoolmomenten hebben) en kunnen zelfs specifiek binden (bijvoorbeeld fosfaat en sulfaat die aan binden). Ionen met een sterk \"inzouteffect\" zoals I\u2212 en SCN\u2212 zijn sterke denatureerders omdat ze de peptidegroep inzouten en dus een sterkere interactie aangaan met de uitgevouwen vorm van een eiwit dan met de oorspronkelijke vorm. Als consequentie verschuiven ze het chemisch evenwicht van de uitvouwreactie naar het ontvouwen eiwit."@nl .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Protein> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Salt_out> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Salt115010703> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA"@ja .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA (Hofmeister series) \u3068\u306F\u3001\u6C34\u3092\u69CB\u9020\u5316\u3055\u305B\u308B\u80FD\u529B\u306E\u9806\u306B\u30A4\u30AA\u30F3\u3092\u914D\u5217\u3057\u305F\u3082\u306E\u3067\u3042\u308B\u3002\u96FB\u89E3\u8CEA\u306B\u3088\u308B\u6C34\u306E\u69CB\u9020\u306E\u5909\u5316\u306F\u3001\u30BF\u30F3\u30D1\u30AF\u8CEA\u306E\u6EB6\u89E3\u5EA6\u306B\u95A2\u3059\u308B\u967D\u30A4\u30AA\u30F3\u304A\u3088\u3073\u9670\u30A4\u30AA\u30F3\u306E\u5F71\u97FF\u306B\u3064\u3044\u3066\u7814\u7A76\u3057\u305F\u30C9\u30A4\u30C4\u306E\u5316\u5B66\u8005\u306B\u3088\u3063\u3066\u521D\u3081\u3066\u89E3\u660E\u3055\u308C\u305F\u3002\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u7CFB\u5217\u3001\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u9806\u5217\u3001\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u5E8F\u5217\u3001\u96E2\u6DB2\u9806\u5217\uFF08\u308A\u3048\u304D\u3058\u3085\u3093\u308C\u3064\u3001Lyotropic series\uFF09\u3068\u3082\u547C\u3070\u308C\u308B\u3002 1888\u5E74\u306B\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u306F\u3001\u9670\u30A4\u30AA\u30F3\u306B\u304A\u3044\u3066\u3001\u5869\u6790\u306B\u8981\u3059\u308B\u6700\u5C0F\u6FC3\u5EA6\u3092\u6BD4\u8F03\u3057\u3001\u6B21\u306E\u3088\u3046\u306A\u9806\u5217\u3092\u5F97\u305F\u3002 \u30AF\u30A8\u30F3\u9178\u30A4\u30AA\u30F3 > \u9152\u77F3\u9178\u30A4\u30AA\u30F3 > \u786B\u9178\u30A4\u30AA\u30F3 > \u9162\u9178\u30A4\u30AA\u30F3 > Cl- > Br- > NO3- > ClO3- > I- > SCN- \u967D\u30A4\u30AA\u30F3\u306F\u3001\u9670\u30A4\u30AA\u30F3\u307B\u3069\u5927\u304D\u306A\u5DEE\u306F\u7121\u3044\u304C\u3001\u3060\u3044\u305F\u3044\u6B21\u306E\u3088\u3046\u306B\u306A\u308B\u3002 \u4E00\u4FA1\u30A4\u30AA\u30F3 Li+ > Na+ > K+ > Rb+ > Cs+\u4E8C\u4FA1\u30A4\u30AA\u30F3 Mg2+ > Ca2+ > Sr2+ > Ba2+ \u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA\u306E\u4ED5\u7D44\u307F\u306F\u307E\u3060\u5B8C\u5168\u306B\u660E\u3089\u304B\u306B\u306A\u3063\u3066\u3044\u306A\u3044\u304C\u3001\u6C34\u305D\u306E\u3082\u306E\u306E\u69CB\u9020\u3068\u3044\u3046\u3088\u308A\u306F\u3001\u30A4\u30AA\u30F3\u3068\u30BF\u30F3\u30D1\u30AF\u8CEA\u3001\u30A4\u30AA\u30F3\u3068\u6C34\u306E\u76F8\u4E92\u4F5C\u7528\u304C\u5909\u5316\u3057\u3066\u3044\u308B\u3068\u8003\u3048\u3089\u308C\u3066\u3044\u308B\u3002 \u3000\u52B9\u679C\u306E\u5927\u304D\u3044\u30A4\u30AA\u30F3\u306F\u6EB6\u6DB2\u306E\u8868\u9762\u5F35\u529B\u3092\u5897\u3057\u3001\u975E\u6975\u6027\u6EB6\u8CEA\u306E\u6EB6\u89E3\u5EA6\u3092\u4E0B\u3052\u308B\u3002\u307E\u305F\u6C34\u306E\u4E71\u96D1\u3055\u3092\u4E0B\u3052\u3066\u758E\u6C34\u52B9\u679C\u3092\u5F37\u3081\u3066\u3044\u308B\u3002"@ja .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Ability105616246> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Material114580897> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"\u041B\u0456\u043E\u0442\u0440\u043E\u043F\u043D\u0438\u0439 \u0440\u044F\u0434 (\u0440\u043E\u0441. \u043B\u0438\u043E\u0442p\u043E\u043F\u043D\u044B\u0439 p\u044F\u0434, [\u0440\u044F\u0434 \u0413\u043E\u0444\u043C\u0435\u0439\u0441\u0442\u0435\u0440\u0430], \u0430\u043D\u0433\u043B. lyotropic [Hofmeister] serie) \u2014 \u0440\u044F\u0434 \u0456\u043E\u043Di\u0432, \u0449\u043E \u0440\u043E\u0437\u0442\u0430\u0448\u043E\u0432\u0430\u043Di \u0432 \u043F\u043E\u0440\u044F\u0434\u043A\u0443 \u043Fi\u0434\u0441\u0438\u043B\u0435\u043D\u043D\u044F \u0447\u0438 \u043F\u043E\u0441\u043B\u0430\u0431\u043B\u0435\u043D\u043D\u044F \u0457\u0445\u043D\u044C\u043E\u0433\u043E \u0432\u043F\u043B\u0438\u0432\u0443 \u043D\u0430 \u0432\u043B\u0430\u0441\u0442\u0438\u0432\u043E\u0441\u0442i \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0438\u043A\u0430 (\u0432'\u044F\u0437\u043A\u0456\u0441\u0442\u044C, \u043F\u043E\u0432\u0435\u0440\u0445\u043D\u0435\u0432\u0438\u0439 \u043D\u0430\u0442\u044F\u0433, \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0456\u0441\u0442\u044C i \u0442. \u043F.), \u0430 \u0442\u0430\u043A\u043E\u0436 \u043D\u0430 \u0448\u0432\u0438\u0434\u043Ai\u0441\u0442\u044C \u0440\u0435\u0430\u043A\u0446i\u0439 \u0443 \u0434\u0430\u043D\u043E\u043C\u0443 \u0440\u043E\u0437\u0447\u0438\u043D\u043D\u0438\u043A\u043E\u0432i \u0442\u0430 i\u043D\u0448i \u0444i\u0437\u0438\u043A\u043E-\u0445\u0456\u043Ci\u0447\u043Di \u043F\u0440\u043E\u0446\u0435\u0441\u0438. \u0421\u0438\u043D\u043E\u043D\u0456\u043C \u2014 \u0440\u044F\u0434 \u0413\u043E\u0444\u043C\u0435\u0439\u0441\u0442\u0435\u0440\u0430."@uk .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Solution114589223> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"De Hofmeister-reeks of lyotropische reeks is een classificatie van ionen op volgorde van hun vermogen om de structuur van water aan te passen. De effecten van deze veranderingen zijn voor het eerst uitgewerkt door , die de effecten van kationen en anionen op de oplosbaarheid van eiwitten bestudeerde. Hofmeister ontdekte een reeks van zouten die consistente effecten hebben op de oplosbaarheid van eiwitten en (zo werd later ontdekt) op de stabiliteit van hun secundaire en tertiaire structuur. Anionen lijken een groter effect te hebben dan kationen en worden gewoonlijk als volgt gesorteerd:"@nl .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageLength>	"9242"^^<http://www.w3.org/2001/XMLSchema#nonNegativeInteger> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://es.dbpedia.org/resource/Serie_de_Hofmeister> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"La Serie de Hofmeister o Serie Liotr\u00F3pica es una clasificaci\u00F3n de los iones en orden de su capacidad para generar precipitaci\u00F3n salina en las prote\u00EDnas.\u200B Los efectos de estos cambios fueron trabajados por primera vez por Franz Hofmeister, quien estudi\u00F3 los efectos de los cationes y aniones en la solubilidad de las prote\u00EDnas\u200B (Esto es un listado parcial ; muchos m\u00E1s las sales han sido estudiadas.)El orden de los cationes podr\u00EDa ser:"@es .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/WikicatSolutions> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Abstraction100002137> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Chemical114806838> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA (Hofmeister series) \u3068\u306F\u3001\u6C34\u3092\u69CB\u9020\u5316\u3055\u305B\u308B\u80FD\u529B\u306E\u9806\u306B\u30A4\u30AA\u30F3\u3092\u914D\u5217\u3057\u305F\u3082\u306E\u3067\u3042\u308B\u3002\u96FB\u89E3\u8CEA\u306B\u3088\u308B\u6C34\u306E\u69CB\u9020\u306E\u5909\u5316\u306F\u3001\u30BF\u30F3\u30D1\u30AF\u8CEA\u306E\u6EB6\u89E3\u5EA6\u306B\u95A2\u3059\u308B\u967D\u30A4\u30AA\u30F3\u304A\u3088\u3073\u9670\u30A4\u30AA\u30F3\u306E\u5F71\u97FF\u306B\u3064\u3044\u3066\u7814\u7A76\u3057\u305F\u30C9\u30A4\u30C4\u306E\u5316\u5B66\u8005\u306B\u3088\u3063\u3066\u521D\u3081\u3066\u89E3\u660E\u3055\u308C\u305F\u3002\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u7CFB\u5217\u3001\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u9806\u5217\u3001\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u5E8F\u5217\u3001\u96E2\u6DB2\u9806\u5217\uFF08\u308A\u3048\u304D\u3058\u3085\u3093\u308C\u3064\u3001Lyotropic series\uFF09\u3068\u3082\u547C\u3070\u308C\u308B\u3002 1888\u5E74\u306B\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u306F\u3001\u9670\u30A4\u30AA\u30F3\u306B\u304A\u3044\u3066\u3001\u5869\u6790\u306B\u8981\u3059\u308B\u6700\u5C0F\u6FC3\u5EA6\u3092\u6BD4\u8F03\u3057\u3001\u6B21\u306E\u3088\u3046\u306A\u9806\u5217\u3092\u5F97\u305F\u3002 \u30AF\u30A8\u30F3\u9178\u30A4\u30AA\u30F3 > \u9152\u77F3\u9178\u30A4\u30AA\u30F3 > \u786B\u9178\u30A4\u30AA\u30F3 > \u9162\u9178\u30A4\u30AA\u30F3 > Cl- > Br- > NO3- > ClO3- > I- > SCN- \u967D\u30A4\u30AA\u30F3\u306F\u3001\u9670\u30A4\u30AA\u30F3\u307B\u3069\u5927\u304D\u306A\u5DEE\u306F\u7121\u3044\u304C\u3001\u3060\u3044\u305F\u3044\u6B21\u306E\u3088\u3046\u306B\u306A\u308B\u3002 \u4E00\u4FA1\u30A4\u30AA\u30F3 Li+ > Na+ > K+ > Rb+ > Cs+\u4E8C\u4FA1\u30A4\u30AA\u30F3 Mg2+ > Ca2+ > Sr2+ > Ba2+ \u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA\u306E\u4ED5\u7D44\u307F\u306F\u307E\u3060\u5B8C\u5168\u306B\u660E\u3089\u304B\u306B\u306A\u3063\u3066\u3044\u306A\u3044\u304C\u3001\u6C34\u305D\u306E\u3082\u306E\u306E\u69CB\u9020\u3068\u3044\u3046\u3088\u308A\u306F\u3001\u30A4\u30AA\u30F3\u3068\u30BF\u30F3\u30D1\u30AF\u8CEA\u3001\u30A4\u30AA\u30F3\u3068\u6C34\u306E\u76F8\u4E92\u4F5C\u7528\u304C\u5909\u5316\u3057\u3066\u3044\u308B\u3068\u8003\u3048\u3089\u308C\u3066\u3044\u308B\u3002 \u3000\u52B9\u679C\u306E\u5927\u304D\u3044\u30A4\u30AA\u30F3\u306F\u6EB6\u6DB2\u306E\u8868\u9762\u5F35\u529B\u3092\u5897\u3057\u3001\u975E\u6975\u6027\u6EB6\u8CEA\u306E\u6EB6\u89E3\u5EA6\u3092\u4E0B\u3052\u308B\u3002\u307E\u305F\u6C34\u306E\u4E71\u96D1\u3055\u3092\u4E0B\u3052\u3066\u758E\u6C34\u52B9\u679C\u3092\u5F37\u3081\u3066\u3044\u308B\u3002 \u52B9\u679C\u306E\u5C0F\u3055\u3044\u3000I\u2212 \u3084 SCN\u2212 \u3001\u30B0\u30A2\u30CB\u30B8\u30A6\u30E0\u306E\u3088\u3046\u306A \u30AB\u30AA\u30C8\u30ED\u30D4\u30C3\u30AF\u30A4\u30AA\u30F3\u3084\u5C3F\u7D20\u306F\u3001\u3080\u3057\u308D\u6C34\u306E\u4E71\u96D1\u3055\u3092\u5897\u3057\u3066\u758E\u6C34\u6027\u76F8\u4E92\u4F5C\u7528\u306B\u3088\u3063\u3066\u6298\u308A\u305F\u305F\u307E\u308C\u305F\u69CB\u9020\u3092\u4F38\u3070\u3057\u305F\u72B6\u614B\u306B\u3059\u308B\u3002\u3057\u304B\u3057\u3001\u3053\u3046\u3057\u3066\u5909\u6027\u3057\u305F\u30BF\u30F3\u30D1\u30AF\u8CEA\u304C\u51DD\u96C6\u3059\u308B\u305F\u3081\u306E\u758E\u6C34\u6027\u76F8\u4E92\u4F5C\u7528\u3082\u5931\u308F\u308C\u305F\u74B0\u5883\u306B\u3042\u308B\u305F\u3081\u3001\u30BF\u30F3\u30D1\u30AF\u8CEA\u306F\u6C88\u6BBF\u3057\u306A\u3044\u3002\u5C3F\u7D20\u306E\u3053\u306E\u52B9\u679C\u306F\u7B49\u96FB\u70B9\u96FB\u6C17\u6CF3\u52D5\u306B\u5229\u7528\u3055\u308C\u3066\u3044\u308B\u3002\u307E\u305F\u306F\u6E29\u548C\u306A\u6761\u4EF6\u3067\u30BF\u30F3\u30D1\u30AF\u8CEA\u3092\u5909\u6027\u3055\u305B\u3064\u3064\u53EF\u6EB6\u5316\u3057\u3066\u3001\u751F\u4F53\u304B\u3089\u6838\u9178\u3092\u5206\u96E2\u3059\u308B\u305F\u3081\u306B\u5229\u7528\u3055\u308C\u3066\u3044\u308B\u3002"@ja .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/WikicatLaboratoryTechniques> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"\u041B\u0456\u043E\u0442\u0440\u043E\u043F\u043D\u0438\u0439 \u0440\u044F\u0434"@uk .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://www.wikidata.org/entity/Q410693> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"Serie de Hofmeister"@es .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://ja.dbpedia.org/resource/\u30DB\u30D5\u30DE\u30A4\u30B9\u30BF\u30FC\u30B7\u30EA\u30FC\u30BA> .
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<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageRevisionID>	"1107245658"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Chemical_equilibrium> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<https://web.archive.org/web/20160304040425/http:/www.cendigital.org/cendigital/20120716%3Fsub_id=FNQ5wyPIC7Sq&folio=42%23pg46> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Franz_Hofmeister> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Reflist> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Die Hofmeister-Reihe (auch Hofmeister-Serie oder Lyotrope Serie) beschreibt die unterschiedlichen F\u00E4llungswirkungen von Salzen. Der Chemiker Franz Hofmeister untersuchte 1888 die proteinf\u00E4llende Wirkung von Salzen und damit der in Wasser gel\u00F6sten Ionen. Er fand dabei empirisch Ionen-Sequenzen, die die St\u00E4rke des Einflusses auf die in Wasser gel\u00F6sten Biomolek\u00FCle charakterisiert."@de .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Mixture114586258> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://xmlns.com/foaf/0.1/isPrimaryTopicOf>	<http://en.wikipedia.org/wiki/Hofmeister_series> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Surface_tension> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Relation100031921> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/abstract>	"The Hofmeister series or lyotropic series is a classification of ions in order of their lyotrophic properties, which is the ability to salt out or salt in proteins. The effects of these changes were first worked out by Franz Hofmeister, who studied the effects of cations and anions on the solubility of proteins. Hofmeister discovered a series of salts that have consistent effects on the solubility of proteins and (it was discovered later) on the stability of their secondary and tertiary structure. Anions appear to have a larger effect than cations, and are usually ordered (This is a partial listing; many more salts have been studied.)The order of cations is usually given as The mechanism of the Hofmeister series is not entirely clear, but does not seem to result from changes in general water structure, instead more specific interactions between ions and proteins and ions and the water molecules directly contacting the proteins may be more important. Recent simulation studies have shown that the variation in solvation energy between the ions and the surrounding water molecules underlies the mechanism of the Hofmeister series. More recently, a quantum chemical investigation suggests an electrostatic origin to the Hofmeister series. This work provides site-centred radial charge densities of the ions' interacting atoms (to approximate the electrostatic potential energy of interaction), and these appear to quantitatively correlate with many reported Hofmeister series for electrolyte properties, reaction rates and macromolecular stability (such as polymer solubility, and virus and enzyme activities). Early members of the series increase solvent surface tension and decrease the solubility of nonpolar molecules (\"salting out\"); in effect, they strengthen the hydrophobic interaction. By contrast, later salts in the series increase the solubility of nonpolar molecules (\"salting in\") and decrease the order in water; in effect, they weaken the hydrophobic effect. The salting out effect is commonly exploited in protein purification through the use of ammonium sulfate precipitation. However, these salts also interact directly with proteins (which are charged and have strong dipole moments) and may even bind specifically (e.g., phosphate and sulfate binding to ribonuclease A). Ions that have a strong 'salting in' effect such as I\u2212 and SCN\u2212 are strong denaturants, because they salt in the peptide group, and thus interact much more strongly with the unfolded form of a protein than with its native form. Consequently, they shift the chemical equilibrium of the unfolding reaction towards unfolded protein. The denaturing of proteins by an aqueous solution containing many types of ions is more complicated as all the ions can act, according to their Hofmeister activity, i.e., a fractional number specifying the position of the ion in the series (given previously) in terms of its relative efficiency in denaturing a reference protein. The concept of Hofmeister ionicity Ih has been invoked by Dharma-wardana et al. where it is proposed to define Ih as a sum over all ionic species, of the product of the ionic concentration (mole fraction) and a fractional number specifying the \"Hofmeister strength\" of the ion in denaturing a given reference protein. The concept of (as a measure of the Hofmeister strength) used here has to be distinguished from ionic strength as used in electrochemistry, and also from its use in the theory of solid semiconductors"@en .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://de.dbpedia.org/resource/Hofmeister-Reihe> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/WikicatSalts> .
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<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Cognition100023271> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Ion> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://yago-knowledge.org/resource/Hofmeister_series> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2002/07/owl#sameAs>	<http://uk.dbpedia.org/resource/\u041B\u0456\u043E\u0442\u0440\u043E\u043F\u043D\u0438\u0439_\u0440\u044F\u0434> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Denaturation_(biochemistry)> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Tertiary_structure> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Matter100020827> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Protein_purification> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Know-how105616786> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"Hofmeister-Reihe"@de .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Hydrophobic_interaction> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Hydrophobic_effect> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Solutions> .
<http://dbpedia.org/resource/Hofmeister_series>	<http://www.w3.org/2000/01/rdf-schema#label>	"Hofmeister-reeks"@nl .
<http://dbpedia.org/resource/Hofmeister_series>	<http://xmlns.com/foaf/0.1/depiction>	<http://commons.wikimedia.org/wiki/Special:FilePath/Prag_Medizinische_Fakult\u00E4t_Franz_Hofmeister_448.jpg> .
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