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Statements

Subject Item
dbr:Vesicle-associated_membrane_protein
rdf:type
yago:PhysicalEntity100001930 yago:Compound114818238 yago:Protein114728724 yago:OrganicCompound114727670 dbo:Protein wikidata:Q206229 wikidata:Q8054 yago:Thing100002452 dbo:Biomolecule yago:Matter100020827 yago:Material114580897 yago:Unit109465459 owl:Thing yago:Part113809207 yago:Relation100031921 yago:Chemical114806838 yago:Macromolecule114944888 yago:WikicatMembraneProteins yago:Abstraction100002137 yago:Molecule114682133 yago:Substance100019613
rdfs:label
Vesicle-associated membrane protein
rdfs:comment
Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion. * VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release. * VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles. * VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis. * VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures. * VAMP7 is found both in secretory granules and endosomes. * VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosom
dbp:name
Synaptobrevin
foaf:depiction
n9:Coresnarecomplex.png
dcterms:subject
dbc:Membrane_proteins
dbo:wikiPageID
2320396
dbo:wikiPageRevisionID
1082980465
dbo:wikiPageWikiLink
dbr:VAMP8 dbr:Exocytosis dbc:Membrane_proteins dbr:VAMP5 dbr:VAMP4 dbr:VAMP2 dbr:VAMP3 dbr:SNARE_(protein) dbr:VAMP1 dbr:Endocytosis dbr:Vesicle_fusion dbr:Synaptobrevin dbr:SYBL1 n20:Hypothetic_models_of_VAMP2_conformations_and_engagement_in_SNARE_complex_assembly_for_neurotransmitter_release.pdf
owl:sameAs
n7:4xWTT dbpedia-gl:Proteína_de_membrana_asociada_a_vesículas yago-res:Vesicle-associated_membrane_protein freebase:m.073kmj wikidata:Q7923214
dbp:wikiPageUsesTemplate
dbt:Short_description dbt:Membrane-protein-stub dbt:Acetylcholine_metabolism_and_transport_modulators dbt:Vesicular_transport_proteins dbt:Membrane_proteins dbt:MeshName dbt:Pfam_box
dbo:thumbnail
n9:Coresnarecomplex.png?width=300
dbp:prosite
PDOC00368
dbp:scop
1
dbp:caption
Three different views of the high resolution structure of a truncated neuronal SNARE complex. Legend: synaptobrevin-2 , Syntaxin-1 , SNAP-25 .
dbp:interpro
IPR016444
dbp:pfam
PF00957
dbp:symbol
Synaptobrevin
dbo:abstract
Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion. * VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release. * VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles. * VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis. * VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures. * VAMP7 is found both in secretory granules and endosomes. * VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells. * VAMP4 is involved in transport from the Golgi.
dbp:membranomeSuperfamily
198
dbp:opmFamily
197
dbp:opmProtein
4
gold:hypernym
dbr:Family
prov:wasDerivedFrom
wikipedia-en:Vesicle-associated_membrane_protein?oldid=1082980465&ns=0
dbo:wikiPageLength
2336
dbo:symbol
Synaptobrevin
foaf:isPrimaryTopicOf
wikipedia-en:Vesicle-associated_membrane_protein