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Statements

Subject Item
dbr:Small_nucleolar_RNA_SNORA68
rdf:type
dbo:ChemicalCompound
rdfs:label
Small nucleolar RNA SNORA68
rdfs:comment
In molecular biology, Small nucleolar RNA SNORA68 (also known as U68) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
dbp:name
U68 Small nucleolar RNA SNORA68
foaf:depiction
n12:RF00263.jpg
dcterms:subject
dbc:Small_nuclear_RNA
dbo:wikiPageID
11421846
dbo:wikiPageRevisionID
1052167752
dbo:wikiPageWikiLink
dbr:Eukaryotic dbr:Secondary_structure dbc:Small_nuclear_RNA dbr:Uridine dbr:HeLa dbr:Eukaryota dbr:Sequence_conservation dbr:Ribosomal_RNA dbr:Small_nucleolar_RNA dbr:Isomerisation dbr:Gene dbr:Pseudouridine dbr:Non-coding_RNA dbr:SnoRNA dbr:Small_nuclear_RNA dbr:Molecular_biology
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wikidata:Q7543264 n15:4uSg9 freebase:m.02rc197
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dbr:Eukaryota
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dbt:Reflist dbt:GO dbt:Small_nucleolar_RNA_SNORA dbt:SnoRNABase dbt:Molecular-cell-biology-stub dbt:Rfam dbt:SO dbt:Infobox_rfam
dbo:thumbnail
n12:RF00263.jpg?width=300
dbp:altsymbols
U68
dbp:caption
Predicted secondary structure and sequence conservation of SNORA68
dbp:id
RF00263 U68
dbp:symbol
SNORA68
dbo:abstract
In molecular biology, Small nucleolar RNA SNORA68 (also known as U68) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA". ACA68 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA68 is predicted to guide the pseudouridylation of U4393 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
dbp:rfam
RF00263
dbp:rnaType
Gene; snRNA; snoRNA; H/ACA-box
gold:hypernym
dbr:Molecule
prov:wasDerivedFrom
wikipedia-en:Small_nucleolar_RNA_SNORA68?oldid=1052167752&ns=0
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2178
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wikipedia-en:Small_nucleolar_RNA_SNORA68