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Statements

Subject Item
dbr:Ribosomal_protein_L20_leader
rdf:type
dbo:Building
rdfs:label
Ribosomal protein L20 leader
rdfs:comment
L20 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of ribosomal proteins L20. The structure is typically located in the 5′ untranslated regions of mRNAs encoding initiation factor 3 followed by ribosomal proteins L35 and L20 (infC-rpmI-rplT), but the regulated mRNAs always contain an L20 gene. A Rho-independent transcription terminator structure that is probably involved in regulation is included at the 3′ end in many examples of L20 ribosomal protein leaders.Three structurally distinct forms of L20 leaders have been experimentally established. One such leader motif occurs in Bacillota and the other two are found in Gammaproteobacteria. Of the latter two, one is found in a wi
dbp:name
L20-Deltaproteobacteria Ribosomal protein L20 leader L20_leader
foaf:depiction
n11:RF00558-rscape.svg n11:RF03126.svg
dcterms:subject
dbc:Ribosomal_protein_leader
dbo:wikiPageID
11421421
dbo:wikiPageRevisionID
1083926769
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dbr:Ribosome_biogenesis dbr:Transcription_(genetics) dbr:Deltaproteobacteria dbr:Bioinformatic dbr:RNA_secondary_structure dbr:Ribosomal_proteins dbr:Sequence_conservation dbr:Bacillota dbr:RNA_motif dbr:Rho_family_of_GTPases dbr:MRNAs dbr:Protein dbr:Ribosomal_protein_leader dbr:Ribosomal_RNA dbr:Gammaproteobacteria dbr:Secondary_structure dbr:Cis-regulatory_element dbr:Escherichia_coli dbc:Ribosomal_protein_leader dbr:Attenuator_(genetics) dbr:Ribosomal_protein
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n11:RF00558-rscape.svg?width=300
dbp:caption
Consensus secondary structure and sequence conservation of Ribosomal protein L20 leader Consensus secondary structure and sequence conservation of L20-Deltaproteobacteria ribosomal protein leader
dbp:id
RF00558
dbp:symbol
L20-Deltaproteobacteria L20_leader
dbo:abstract
L20 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of ribosomal proteins L20. The structure is typically located in the 5′ untranslated regions of mRNAs encoding initiation factor 3 followed by ribosomal proteins L35 and L20 (infC-rpmI-rplT), but the regulated mRNAs always contain an L20 gene. A Rho-independent transcription terminator structure that is probably involved in regulation is included at the 3′ end in many examples of L20 ribosomal protein leaders.Three structurally distinct forms of L20 leaders have been experimentally established. One such leader motif occurs in Bacillota and the other two are found in Gammaproteobacteria. Of the latter two, one is found in a wide variety of Gammaproteobacteria, while the other is only reported in Escherichia coli. All three types of leader exhibit apparent similarities to the region of Ribosomal RNA to which the L20 protein normally binds. However, in terms of RNA secondary structure, the context of the similar region is distinct in each leader type. A fourth example of an L20 ribosomal protein leader was predicted in Deltaproteobacteria using bioinformatic approaches.Like the three experimentally validated kinds of leader, the Deltaproteobacterial version resembles the relevant portion of ribosomal RNA, but presents this similarity in yet another structural context.
dbp:rfam
RF00558 RF03126
dbp:rnaType
dbr:Attenuator_(genetics) dbr:Cis-regulatory_element
gold:hypernym
dbr:Structure
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wikipedia-en:Ribosomal_protein_L20_leader?oldid=1083926769&ns=0
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wikipedia-en:Ribosomal_protein_L20_leader