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Statements

Subject Item
dbr:Prevotella-2_RNA_motif
rdfs:label
Prevotella-2 RNA motif
rdfs:comment
The Prevotella-2 RNA motif is a conserved RNA structure that was discovered by bioinformatics.Energetically stable tetraloops often occur in this motif.Prevotella-2 motif RNAs are found in the bacterial genus Prevotella.
dbp:name
Prevotella-2
foaf:depiction
n12:RF03043.svg
dcterms:subject
dbc:Non-coding_RNA
dbo:wikiPageID
58276326
dbo:wikiPageRevisionID
1059163776
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dbr:Cis-regulatory_element dbr:RNA dbr:Bacteria dbr:Prevotella dbr:Secondary_structure dbr:Sequence_conservation dbr:Proton dbr:DNA_strand dbr:Tetraloop dbr:Small_RNA dbr:Secretion dbr:Intrinsic_termination dbr:Sodium dbr:Gene dbr:Bioinformatics_discovery_of_non-coding_RNAs dbr:Genus dbc:Non-coding_RNA
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n12:RF03043.svg?width=300
dbp:caption
Consensus secondary structure and sequence conservation of Prevotella-2 RNA
dbp:symbol
Prevotella-2
dbo:abstract
The Prevotella-2 RNA motif is a conserved RNA structure that was discovered by bioinformatics.Energetically stable tetraloops often occur in this motif.Prevotella-2 motif RNAs are found in the bacterial genus Prevotella. Nearly all Prevotella-2 RNAs occur upstream of genes that encode sodium/proton antiporters. These data suggest that the RNAs function as cis-regulatory elements. However, one Prevotella-2 RNA is located upstream of a gene encoded on the opposite DNA strand, which would be unlikely for a cis-regulatory function in bacteria. Therefore, it is also possible that Prevotella-2 RNAs are small RNAs that operate in trans. In this model, their association with sodium/proton antiporters would be a coincidence. Most Prevotella-2 RNAs are followed by a Rho-independent transcription terminator. If the RNAs function in cis, these transcript terminators might be a part of the mechanism used to achieve gene regulation. If, on the other hand, Prevotella-2 RNAs correspond to small RNAs, the terminators may simply terminate the transcript containing this non-coding RNA.
dbp:rfam
RF03043
dbp:rnaType
dbr:Gene dbr:Small_RNA
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wikipedia-en:Prevotella-2_RNA_motif?oldid=1059163776&ns=0
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2341
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wikipedia-en:Prevotella-2_RNA_motif