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Hemoreologia Hemorheology ヘモレオロジー
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Hemorheology, also spelled haemorheology (from the Greek ‘αἷμα, haima "blood" and rheology [from Greek ῥέω rhéō, "flow" and -λoγία, -logia, "study of"]), or blood rheology, is the study of flow properties of blood and its elements of plasma and cells. Proper tissue perfusion can occur only when blood's rheological properties are within certain levels. Alterations of these properties play significant roles in disease processes. Blood viscosity is determined by plasma viscosity, hematocrit (volume fraction of red blood cell, which constitute 99.9% of the cellular elements) and mechanical properties of red blood cells. Red blood cells have unique mechanical behavior, which can be discussed under the terms erythrocyte deformability and erythrocyte aggregation. Because of that, blood behaves as ヘモレオロジー(英: hemorheology) または 血液レオロジー (英: blood rheology)とは、血液とその構成要素(血漿や血球など)の流体としての性質を研究するレオロジーの一分野である。血液の適切な組織灌流は、血液の流動学的性質が適正な範囲内にあることにより得られる。これら流動学的性質の変動は疾患の病態生理において重要な役割を果たしている。血液の粘度を決定する要因は、血漿の粘度、ヘマトクリット、そして赤血球の力学的性質である。赤血球は、そのとの観点から,力学的に特有の振る舞いを示すことで知られている。そのため、血液は非ニュートン流体として振る舞う。 非ニュートン流体としての血液の性質を示すものとして、血液の粘度は(ずり速度)に応じて変わる。心臓の最大収縮期のように剪断速度が高い状況では血液の粘度は下がり、一方拡張末期で血流速度が下がると血液の粘度は上昇する。それ故、血液はを持つ流体であると言える。 Hemoreologia (gr. haima, krew; rhoia, przepływ; logos, science) — nauka zajmująca się badaniem wpływu ciśnienia płynącej krwi na jej elementy komórkowe oraz na ściany naczyń krwionośnych. Hemoreologia obejmuje zagadnienia dotyczące przepływu krwi oraz odkształcenia jej elementów (tj. krwinek czerwonych, białych krwinek i płytek krwi). Badania właściwości reologicznych krwi są zarówno nauką podstawową, jak i obszarem zainteresowania klinicznego, gdyż właściwości te ulegają zmianom w wielu stanach chorobowych. Coraz większa liczba danych wyraźnie wskazuje, że właściwości przepływowe krwi są jednym z podstawowych wyznaczników prawidłowej perfuzji tkanek.
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Hemorheology, also spelled haemorheology (from the Greek ‘αἷμα, haima "blood" and rheology [from Greek ῥέω rhéō, "flow" and -λoγία, -logia, "study of"]), or blood rheology, is the study of flow properties of blood and its elements of plasma and cells. Proper tissue perfusion can occur only when blood's rheological properties are within certain levels. Alterations of these properties play significant roles in disease processes. Blood viscosity is determined by plasma viscosity, hematocrit (volume fraction of red blood cell, which constitute 99.9% of the cellular elements) and mechanical properties of red blood cells. Red blood cells have unique mechanical behavior, which can be discussed under the terms erythrocyte deformability and erythrocyte aggregation. Because of that, blood behaves as a non-Newtonian fluid. As such, the viscosity of blood varies with shear rate. Blood becomes less viscous at high shear rates like those experienced with increased flow such as during exercise or in peak-systole. Therefore, blood is a shear-thinning fluid. Contrarily, blood viscosity increases when shear rate goes down with increased vessel diameters or with low flow, such as downstream from an obstruction or in diastole. Blood viscosity also increases with increases in red cell aggregability. Hemoreologia (gr. haima, krew; rhoia, przepływ; logos, science) — nauka zajmująca się badaniem wpływu ciśnienia płynącej krwi na jej elementy komórkowe oraz na ściany naczyń krwionośnych. Hemoreologia obejmuje zagadnienia dotyczące przepływu krwi oraz odkształcenia jej elementów (tj. krwinek czerwonych, białych krwinek i płytek krwi). Badania właściwości reologicznych krwi są zarówno nauką podstawową, jak i obszarem zainteresowania klinicznego, gdyż właściwości te ulegają zmianom w wielu stanach chorobowych. Coraz większa liczba danych wyraźnie wskazuje, że właściwości przepływowe krwi są jednym z podstawowych wyznaczników prawidłowej perfuzji tkanek. ヘモレオロジー(英: hemorheology) または 血液レオロジー (英: blood rheology)とは、血液とその構成要素(血漿や血球など)の流体としての性質を研究するレオロジーの一分野である。血液の適切な組織灌流は、血液の流動学的性質が適正な範囲内にあることにより得られる。これら流動学的性質の変動は疾患の病態生理において重要な役割を果たしている。血液の粘度を決定する要因は、血漿の粘度、ヘマトクリット、そして赤血球の力学的性質である。赤血球は、そのとの観点から,力学的に特有の振る舞いを示すことで知られている。そのため、血液は非ニュートン流体として振る舞う。 非ニュートン流体としての血液の性質を示すものとして、血液の粘度は(ずり速度)に応じて変わる。心臓の最大収縮期のように剪断速度が高い状況では血液の粘度は下がり、一方拡張末期で血流速度が下がると血液の粘度は上昇する。それ故、血液はを持つ流体であると言える。
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