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The TBP-associated factors (TAF) are proteins that associate with the TATA-binding protein in transcription initiation. It is a part of the transcription initiation factor TFIID multimeric protein complex. It also makes up many other factors, including SL1. They mediate the formation of the transcription preinitiation complex, a step preceding transcription of DNA to RNA by RNA polymerase II. TAFs have a signature N-terminal histone-like fold domain (HFD). This domain is implicated in the pairwise interaction among specific TAFs.

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dbo:abstract
  • The TBP-associated factors (TAF) are proteins that associate with the TATA-binding protein in transcription initiation. It is a part of the transcription initiation factor TFIID multimeric protein complex. It also makes up many other factors, including SL1. They mediate the formation of the transcription preinitiation complex, a step preceding transcription of DNA to RNA by RNA polymerase II. TAFs have a signature N-terminal histone-like fold domain (HFD). This domain is implicated in the pairwise interaction among specific TAFs. (en)
dbo:symbol
  • TAF
  • TAF1_subA
  • TAF4
  • TAFH
  • TFIID-18kDa
  • TFIID-31kDa
dbo:thumbnail
dbo:wikiPageID
  • 36518828 (xsd:integer)
dbo:wikiPageLength
  • 7206 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1045643617 (xsd:integer)
dbo:wikiPageWikiLink
dbp:caption
  • drosophila dtafii42/dtafii62 heterotetramer, HFD (en)
dbp:interpro
  • IPR007900 (en)
  • IPR003162 (en)
  • IPR003195 (en)
  • IPR003894 (en)
  • IPR004823 (en)
  • IPR039495 (en)
dbp:name
  • TAF (en)
  • TAF13 (en)
  • TAF4 (en)
  • TAF RNA Polymerase I subunit A (en)
  • TAF/Nervy homology (en)
  • TAFII31 (en)
  • TBP associated factor (en)
dbp:pfam
  • PF04719 (en)
  • PF05236 (en)
  • PF02269 (en)
  • PF02291 (en)
  • PF02969 (en)
  • PF03540 (en)
  • PF03847 (en)
  • PF07531 (en)
  • PF14929 (en)
dbp:pfamClan
  • CL0012 (en)
dbp:scop
  • 1 (xsd:integer)
dbp:smart
  • TAFH (en)
dbp:symbol
  • TAF (en)
  • TAF4 (en)
  • TAFH (en)
  • TAF1_subA (en)
  • TFIID-18kDa (en)
  • TFIID-31kDa (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • The TBP-associated factors (TAF) are proteins that associate with the TATA-binding protein in transcription initiation. It is a part of the transcription initiation factor TFIID multimeric protein complex. It also makes up many other factors, including SL1. They mediate the formation of the transcription preinitiation complex, a step preceding transcription of DNA to RNA by RNA polymerase II. TAFs have a signature N-terminal histone-like fold domain (HFD). This domain is implicated in the pairwise interaction among specific TAFs. (en)
rdfs:label
  • TBP-associated factor (en)
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