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Serapio Rukundo is a Ugandan accountant and politician. He was the State Minister for Tourism and Wildlife in the Ugandan Cabinet, from 1 June 2006 until 27 May 2011. In the cabinet reshuffle of 27 May 2011, he was dropped from the cabinet and replaced by Agnes Akiror. He also served as the elected Member of Parliament representing Kabale Municipality from 2001 until 2011. During the 2011 national election cycle, he lost the Kabale Municipality parliamentary seat to Andrew Baryayanga.