| dbo:abstract
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- The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease. The Mouse Models of Human Cancer database (MMHCdb) is a unique, comprehensive online knowledgebase of mouse models of human cancer hosted by The Jackson Laboratory with funding from the National Cancer Institute (NCI). MMHCdb is part of the Mouse Genome Informatics consortium (MGI) and was first released in 1998 as the Mouse Tumor Biology (MTB) database. MMHCdb contains genetic and genomic information about inbred mouse strains, genetically engineered mouse models (GEMMs) and Patient Derived Xenograft (PDX) models of human cancer. Data in MMHCdb is expertly curated from peer-reviewed scientific publications or obtained as direct data submissions from individual investigators and large-scale research initiatives. MMHCdb, in collaboration with EMBL-EBI, co-developed the PDX Finder resource which serves as a global catalog of PDX models. (en)
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| dbo:title
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- Mouse Models of Human Cancer database (en)
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- 9450 (xsd:nonNegativeInteger)
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| dbp:citation
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- Krupke et al. PMID: 29092943 (en)
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| dbp:description
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- Resource for information on mouse models of human cancer. (en)
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| dbp:logo
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| dbp:organism
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- Mus musculus, Homo sapiens (en)
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| dbp:scope
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- Mouse models, genetics, genomics, tumor pathology images. (en)
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| dbp:title
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- Mouse Models of Human Cancer database (en)
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| dbp:wikiPageUsesTemplate
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| dc:description
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- Resource for information on mouse models of human cancer.
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| rdfs:comment
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- The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease. (en)
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| rdfs:label
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- Mouse Models of Human Cancer database (en)
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| is foaf:primaryTopic
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