dbo:abstract
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- Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. In contrast to hydrocodone/acetaminophen combination analgesics such as Vicodin, this hydrocodone/ibuprofen avoids some of the liver toxicity which may occur from acetaminophen, but still presents significant dangers in hydrocodone overdose, namely respiratory depression. Vicoprofen is supplied in a fixed dose combination tablet which contains hydrocodone bitartrate, USP 7.5 mg with ibuprofen, USP 200 mg. Additional strengths of generic Vicoprofen are now available, in combinations of 5 mg/200 mg and 10 mg/200 mg respectively. (en)
- Le Vicoprofen est le nom commercial d'une association d'hydrocodone et d'ibuprofène, disponible aux Etats-Unis. L'hydrocodone appartient au groupe des médicaments analgésiques stupéfiants. L'ibuprofène est un anti-inflammatoire non stéroïdien (AINS), qui agit en réduisant les hormones qui provoquent l'inflammation et la douleur dans le corps. Le Vicoprofen est utilisé à court terme (10 jours maximum) pour soulager la douleur, par exemple après une opération dentaire. Ce médicament n'est donc pas indiqué pour le traitement de la douleur chronique, par exemple arthritique. Cette limitation de durée est supposée éviter les effets addictifs de l'hydrocodone. (fr)
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dbo:alternativeName
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- Ibudone, Reprexain, Vicoprofen (en)
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- 16248 (xsd:nonNegativeInteger)
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dbp:casNumber
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- 15687 (xsd:integer)
- 615580 (xsd:integer)
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dbp:class
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dbp:component
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- Ibuprofen (en)
- Hydrocodone (en)
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dbp:dailymedid
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- Hydrocodone_and_ibuprofen (en)
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dbp:dependencyLiability
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dbp:eliminationHalfLife
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dbp:excretion
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- for hydrocodone: urinary; for ibuprofen: urine primarily (en)
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dbp:legalStatus
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dbp:legalUs
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dbp:licenceUs
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dbp:metabolism
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- for hydrocodone: liver, CYP3A4; for ibuprofen: liver, CYP2C9 (en)
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dbp:pubchemsubstance
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dbp:tradename
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- Ibudone, Reprexain, Vicoprofen (en)
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dbp:type
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dbp:unii
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- 6 (xsd:integer)
- WK2XYI10QM (en)
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rdfs:comment
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- Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. In contrast to hydrocodone/acetaminophen combination analgesics such as Vicodin, this hydrocodone/ibuprofen avoids some of the liver toxicity which may occur from acetaminophen, but still presents significant dangers in hydrocodone overdose, namely respiratory depression. Vicoprofen is supplied in a fixed dose combination tablet which contains hydrocodone bitartrate, USP 7.5 mg with ibuprofen, USP 200 mg. Additional strengths of generic Vicoprofen are now available, in co (en)
- Le Vicoprofen est le nom commercial d'une association d'hydrocodone et d'ibuprofène, disponible aux Etats-Unis. L'hydrocodone appartient au groupe des médicaments analgésiques stupéfiants. L'ibuprofène est un anti-inflammatoire non stéroïdien (AINS), qui agit en réduisant les hormones qui provoquent l'inflammation et la douleur dans le corps. (fr)
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rdfs:label
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- Vicoprofen (fr)
- Hydrocodone/ibuprofen (en)
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