An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Hexylresorcinol is an organic compound with local anaesthetic, antiseptic, and anthelmintic properties. It is available for use topically on small skin infections, or as an ingredient in throat lozenges. It is marketed as S.T.37 by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as an antiseptic. Sytheon Ltd., USA markets hexylresorcinol (trade named Synovea HR). Johnson & Johnson uses hexylresorcinol in its Neutrogena, Aveno, and RoC skincare products as an anti-aging cream. Hexylresorcinol has been used commercially by many cosmetic and personal care companies, such as Mary Kay, Clarins, Unilever, Murad, , Arbonne, and many small and large companies. As an anthelmintic, hexylresorcinol was sold under the brand Crystoids.

Property Value
dbo:abstract
  • 4-Hexylresorcin leitet sich formal vom Resorcin ab. An Position 4 befindet sich ein Hexylrest. Als Lebensmittelzusatzstoff trägt es in der Europäischen Union die Bezeichnung E 586. (de)
  • Hexylresorcinol is an organic compound with local anaesthetic, antiseptic, and anthelmintic properties. It is available for use topically on small skin infections, or as an ingredient in throat lozenges. It is marketed as S.T.37 by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as an antiseptic. Sytheon Ltd., USA markets hexylresorcinol (trade named Synovea HR). Johnson & Johnson uses hexylresorcinol in its Neutrogena, Aveno, and RoC skincare products as an anti-aging cream. Hexylresorcinol has been used commercially by many cosmetic and personal care companies, such as Mary Kay, Clarins, Unilever, Murad, , Arbonne, and many small and large companies. As an anthelmintic, hexylresorcinol was sold under the brand Crystoids. A study published in Chemical Research in Toxicology shows that 4-hexylresorcinol used as a food additive (E-586) exhibits some estrogenic activity, i.e. resembles action of the female sex hormone estrogen. However, recent study published in Applied Sciences shows that 4-hexylresorcinol did not change the expression of estrogen receptor-α, -β, or p-ERK1/2 in MCF-7 cells. In an ovariectomized animal model, the 4HR group showed similar levels of ERα, ERβ, and prolactin expression in the pituitary gland compared to the solvent only group, while the estradiol group showed higher levels. Serum prolactin levels were similar between the 4HR and solvent only groups. In one study, 4-hexylresorcinol increased the shelf life of shrimp by reducing melanosis (black spots). In mice with cancer, 4-hexylresorcinol inhibited NF-κB and extended their survival rate. (en)
  • L'esilresorcinolo è un composto organico con proprietà anestetiche, antisettiche e antielmintiche utilizzato topicamente per le infezioni della cute e come sciroppo per la faringite. È stato studiato come adiuvante del cisplatino nel trattamento antitumorale, dimostrando una maggior efficacia dell'antitumorale somministrato da solo È stato valutato anche come antisettico nell'impianto di protesi dentarie. Uno studio del 2009 ha mostrato che l'esilresorcinolo utilizzato come additivo alimentare (E-586) ha attività estrogeniche simili agli ormoni sessuali femminili. (it)
  • ヘキシルレゾルシノール(Hexylresorcinol)は、麻酔薬、殺菌剤、駆虫薬としての性質を持つ有機化合物である。 局所的で小さなの治療やトローチの成分として用いられる。 2014年6月20日現在、EU圏では酸化防止剤の1つ(E-586)として許可されている。しかし、Chemical Research in Toxicology誌に掲載された研究では、4-ヘキシルレゾルシノールを食品添加物(E-586)として用いると、エストロゲン様の作用を示すことが示された。 (ja)
  • 4-hexylresorcinol of 4-hexyl-benzeen-1,3-diol is een organische verbinding met als brutoformule C12H18O2. De stof komt voor als een wit poeder, dat zeer slecht oplosbaar is in water, maar goed oplosbaar in di-ethylether en aceton. 4-hexylresorcinol wordt toegevoegd aan bepaalde geneesmiddelen voor uitwendig gebruik als antiseptisch middel. Het is ook een alternatief voor sulfiet om de bruinkleuring van garnalen en andere schaaldieren tegen te gaan. Voor deze toepassing is 4-hexylresorcinol in de Europese Unie sedert juli 2006 toegelaten als voedingsadditief met het E-nummer E586. Het restgehalte aan 4-hexylresorcinol in het vlees van de schaaldieren mag niet meer zijn dan 2 mg/kg. (nl)
  • 4-Hexilresorcinol ou 4-hexilbenzen-1,3-diol é um composto orgânico com propriedades anestésicas, antissépticas e anti-heelmínticas. (pt)
  • Гексилрезорцин (1,3-диокси-4-н-гексилбензол) — противоглистное и бактерицидное средство. (ru)
  • Heksylorezorcynol – organiczny związek chemiczny z grupy alkilorezorcynoli, lek o działaniu antyseptycznym, przeciwpasożytniczym i miejscowo znieczulającym. (pl)
  • 4-己基间苯二酚(英語:4-Hexylresorcinol,也称作己雷琐辛或4-己基-1,3-苯二酚)是一种烷基间苯二酚类化合物,常用作、消毒藥和局部麻醉药。 (zh)
dbo:alternativeName
  • Crystoids (en)
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  • 136-77-6
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  • 443605
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  • R9QTB5E82N
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  • D04441
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  • 3610
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  • Hexylresorcinol-3D-balls.png (en)
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  • Oc1ccccc1CCCCCC (en)
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  • Crystoids (en)
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  • 4-Hexylresorcin leitet sich formal vom Resorcin ab. An Position 4 befindet sich ein Hexylrest. Als Lebensmittelzusatzstoff trägt es in der Europäischen Union die Bezeichnung E 586. (de)
  • L'esilresorcinolo è un composto organico con proprietà anestetiche, antisettiche e antielmintiche utilizzato topicamente per le infezioni della cute e come sciroppo per la faringite. È stato studiato come adiuvante del cisplatino nel trattamento antitumorale, dimostrando una maggior efficacia dell'antitumorale somministrato da solo È stato valutato anche come antisettico nell'impianto di protesi dentarie. Uno studio del 2009 ha mostrato che l'esilresorcinolo utilizzato come additivo alimentare (E-586) ha attività estrogeniche simili agli ormoni sessuali femminili. (it)
  • ヘキシルレゾルシノール(Hexylresorcinol)は、麻酔薬、殺菌剤、駆虫薬としての性質を持つ有機化合物である。 局所的で小さなの治療やトローチの成分として用いられる。 2014年6月20日現在、EU圏では酸化防止剤の1つ(E-586)として許可されている。しかし、Chemical Research in Toxicology誌に掲載された研究では、4-ヘキシルレゾルシノールを食品添加物(E-586)として用いると、エストロゲン様の作用を示すことが示された。 (ja)
  • 4-Hexilresorcinol ou 4-hexilbenzen-1,3-diol é um composto orgânico com propriedades anestésicas, antissépticas e anti-heelmínticas. (pt)
  • Гексилрезорцин (1,3-диокси-4-н-гексилбензол) — противоглистное и бактерицидное средство. (ru)
  • Heksylorezorcynol – organiczny związek chemiczny z grupy alkilorezorcynoli, lek o działaniu antyseptycznym, przeciwpasożytniczym i miejscowo znieczulającym. (pl)
  • 4-己基间苯二酚(英語:4-Hexylresorcinol,也称作己雷琐辛或4-己基-1,3-苯二酚)是一种烷基间苯二酚类化合物,常用作、消毒藥和局部麻醉药。 (zh)
  • Hexylresorcinol is an organic compound with local anaesthetic, antiseptic, and anthelmintic properties. It is available for use topically on small skin infections, or as an ingredient in throat lozenges. It is marketed as S.T.37 by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as an antiseptic. Sytheon Ltd., USA markets hexylresorcinol (trade named Synovea HR). Johnson & Johnson uses hexylresorcinol in its Neutrogena, Aveno, and RoC skincare products as an anti-aging cream. Hexylresorcinol has been used commercially by many cosmetic and personal care companies, such as Mary Kay, Clarins, Unilever, Murad, , Arbonne, and many small and large companies. As an anthelmintic, hexylresorcinol was sold under the brand Crystoids. (en)
  • 4-hexylresorcinol of 4-hexyl-benzeen-1,3-diol is een organische verbinding met als brutoformule C12H18O2. De stof komt voor als een wit poeder, dat zeer slecht oplosbaar is in water, maar goed oplosbaar in di-ethylether en aceton. (nl)
rdfs:label
  • 4-Hexylresorcin (de)
  • Esilresorcinolo (it)
  • Hexylresorcinol (en)
  • ヘキシルレゾルシノール (ja)
  • 4-hexylresorcinol (nl)
  • Heksylorezorcynol (pl)
  • 4-Hexilresorcinol (pt)
  • Гексилрезорцин (ru)
  • 4-己基间苯二酚 (zh)
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