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Geosmin synthase or germacradienol-geosmin synthase designates a class of bifunctional enzymes (EC 4.1.99.16) that catalyze the conversion of farnesyl diphosphate (FPP) to geosmin, a volatile organic compound known for its earthy smell. The N-terminal half of the protein catalyzes the conversion of farnesyl diphosphate to and germacrene D, followed by the C-terminal-mediated conversion of germacradienol to geosmin. The conversion of FPP to geosmin was previously thought to involve multiple enzymes in a biosynthetic pathway.

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dbo:abstract
  • Geosmin synthase or germacradienol-geosmin synthase designates a class of bifunctional enzymes (EC 4.1.99.16) that catalyze the conversion of farnesyl diphosphate (FPP) to geosmin, a volatile organic compound known for its earthy smell. The N-terminal half of the protein catalyzes the conversion of farnesyl diphosphate to and germacrene D, followed by the C-terminal-mediated conversion of germacradienol to geosmin. The conversion of FPP to geosmin was previously thought to involve multiple enzymes in a biosynthetic pathway. (en)
dbo:ecNumber
  • 4.1.99.16
dbo:thumbnail
dbo:wikiPageID
  • 38551708 (xsd:integer)
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  • 14627 (xsd:nonNegativeInteger)
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  • 1123481845 (xsd:integer)
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dbp:caption
  • Predicted streptomyces is a mycelial forming Actinomycete which lives in soil,they impart 'earthy odor' to soil after rain which is due to the presence of gemstones.- This point was given by s.lokeshwar 007 structure of Geosmin Synthae from I-TASSER prediction (en)
dbp:chromosome
  • genome (en)
dbp:ecNumber
  • 4.100000 (xsd:double)
dbp:ecnumber
  • 4.100000 (xsd:double)
dbp:entrezchromosome
  • NC_003155.4 (en)
dbp:entrezgene
  • 1210359 (xsd:integer)
dbp:genlocEnd
  • 2638086 (xsd:integer)
dbp:genlocStart
  • 2635255 (xsd:integer)
dbp:interpro
  • IPR005630 (en)
dbp:iubmbEcNumber
  • 4 (xsd:integer)
dbp:name
  • Geosmin synthase (en)
  • Germacradienol synthase (en)
  • Terpene synthase family, metal binding domain (en)
dbp:organism
  • Streptomyces avermitilis (en)
dbp:pfam
  • PF03936 (en)
dbp:refseqmrna
  • BA000030.3 (en)
dbp:refseqprotein
  • BAC69874.1 (en)
dbp:scop
  • 5 (xsd:integer)
dbp:symbol
  • Terpene_synth_C (en)
  • geoA (en)
dbp:taxid
  • 33903 (xsd:integer)
dbp:uniprot
  • Q82L49 (en)
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rdfs:comment
  • Geosmin synthase or germacradienol-geosmin synthase designates a class of bifunctional enzymes (EC 4.1.99.16) that catalyze the conversion of farnesyl diphosphate (FPP) to geosmin, a volatile organic compound known for its earthy smell. The N-terminal half of the protein catalyzes the conversion of farnesyl diphosphate to and germacrene D, followed by the C-terminal-mediated conversion of germacradienol to geosmin. The conversion of FPP to geosmin was previously thought to involve multiple enzymes in a biosynthetic pathway. (en)
rdfs:label
  • Geosmin synthase (en)
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foaf:name
  • Geosmin synthase (en)
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