About: Fosphenytoin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin.

Property Value
dbo:abstract
  • Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin. (en)
dbo:alternativeName
  • Cerebyx (en)
dbo:bioavailability
  • 100.000000 (xsd:float)
dbo:casNumber
  • 93390-81-9
dbo:chEMBL
  • 919
dbo:drugbank
  • DB01320
dbo:fdaUniiCode
  • B4SF212641
dbo:kegg
  • D07993
dbo:medlinePlus
  • a604036
dbo:pubchem
  • 56339
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dbp:atcPrefix
  • N03 (en)
dbp:atcSuffix
  • AB05 (en)
dbp:bioavailability
  • 100.0
dbp:c
  • 16 (xsd:integer)
dbp:casNumber
  • 93390 (xsd:integer)
dbp:chembl
  • 919 (xsd:integer)
dbp:chemspiderid
  • 50839 (xsd:integer)
dbp:dailymedid
  • Fosphenytoin (en)
dbp:drugbank
  • DB01320 (en)
dbp:eliminationHalfLife
  • 900.0
dbp:excretion
dbp:h
  • 15 (xsd:integer)
dbp:image
  • Fosphenytoin 3D ball.png (en)
dbp:iupacName
  • methoxyphosphonic acid (en)
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  • 7190 (xsd:integer)
dbp:kegg
  • D07993 (en)
dbp:legalStatus
  • Rx-only (en)
dbp:legalUs
  • Rx-only (en)
dbp:medlineplus
  • a604036 (en)
dbp:metabolism
dbp:n
  • 2 (xsd:integer)
dbp:o
  • 6 (xsd:integer)
dbp:p
  • 1 (xsd:integer)
dbp:pregnancyUs
  • D (en)
dbp:proteinBound
  • 95 (xsd:integer)
dbp:pubchem
  • 56339 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • O=C3NCOPO (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • XWLUWCNOOVRFPX-UHFFFAOYSA-N (en)
dbp:tradename
  • Cerebyx (en)
dbp:unii
  • B4SF212641 (en)
dbp:verifiedfields
  • changed (en)
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  • 461113778 (xsd:integer)
dbp:watchedfields
  • changed (en)
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  • 175 (xsd:integer)
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rdfs:comment
  • Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin. (en)
rdfs:label
  • Fosphenytoin (en)
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