About: CAMK

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CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca2+) and calmodulin. When activated, the enzymes transfer phosphates from ATP to defined serine or threonine residues in other proteins, so they are serine/threonine-specific protein kinases. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms involved in the learning and memory of an organism.

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  • CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca2+) and calmodulin. When activated, the enzymes transfer phosphates from ATP to defined serine or threonine residues in other proteins, so they are serine/threonine-specific protein kinases. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms involved in the learning and memory of an organism. (en)
  • Les protéine kinases Ca2+/calmoduline-dépendantes ou CaM kinases sont des kinases Sérine-Thréonine-dépendantes régulées par le complexe Ca2+/calmoduline. La CaMKII est impliquée dans de nombreuses cascades de signalisation, et est un médiateur putatif important de l'apprentissage et de la mémoire. La CaMKII est aussi nécessaire pour l'homéostasie calcique, et la recapture du calcium dans les cardiomyocytes le transport d'ions chlore dans les épithéliums, la sélection positive des cellules T, et l'activation des cellules T CD8. Il existe une corrélation entre une mauvaise régulation de la CaMKII et la maladie d'Alzheimer, le syndrome d'Angelman, et l'arythmie cardiaque (références 1 et 3). (fr)
  • 钙离子/钙调素依赖的蛋白激酶或钙调蛋白激酶(英文:Ca2+/calmodulin-dependent protein kinases or CaM kinases )是一种丝氨酸/苏氨酸特性的蛋白激酶,被钙/钙调蛋白复合物所调节。这个种系的蛋白在活化時表現出一種记忆效应。 (zh)
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  • 2.7.11.17
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  • 97350 (xsd:integer)
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  • Ca2+/calmodulin-dependent protein kinase (en)
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  • CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca2+) and calmodulin. When activated, the enzymes transfer phosphates from ATP to defined serine or threonine residues in other proteins, so they are serine/threonine-specific protein kinases. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms involved in the learning and memory of an organism. (en)
  • Les protéine kinases Ca2+/calmoduline-dépendantes ou CaM kinases sont des kinases Sérine-Thréonine-dépendantes régulées par le complexe Ca2+/calmoduline. La CaMKII est impliquée dans de nombreuses cascades de signalisation, et est un médiateur putatif important de l'apprentissage et de la mémoire. La CaMKII est aussi nécessaire pour l'homéostasie calcique, et la recapture du calcium dans les cardiomyocytes le transport d'ions chlore dans les épithéliums, la sélection positive des cellules T, et l'activation des cellules T CD8. Il existe une corrélation entre une mauvaise régulation de la CaMKII et la maladie d'Alzheimer, le syndrome d'Angelman, et l'arythmie cardiaque (références 1 et 3). (fr)
  • 钙离子/钙调素依赖的蛋白激酶或钙调蛋白激酶(英文:Ca2+/calmodulin-dependent protein kinases or CaM kinases )是一种丝氨酸/苏氨酸特性的蛋白激酶,被钙/钙调蛋白复合物所调节。这个种系的蛋白在活化時表現出一種记忆效应。 (zh)
rdfs:label
  • CAMK (en)
  • Protéine kinase Ca2+/calmoduline-dépendante (fr)
  • 钙离子/钙调素依赖性蛋白激酶 (zh)
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  • Ca2+/calmodulin-dependent protein kinase (en)
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