Bernard Peyrilhe (1735–1804) was a French surgeon, known as one of the founders of experimental cancer research. Peyrilhe was born in Pompignan, and became a lecturer at the Paris School of Surgery (École de Chirurgie). Also in 1773, Peyrihle was the first surgeon to treat breast cancer by radical mastectomy which included both the pectoral muscle and axillary lymph nodes. He considered that the risks of amputating the pectoral muscle were outweighed by the otherwise certain outcome of death.
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