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α-Isocomene synthase (EC 4.2.3.136, MrTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (–)-α-isocomene-forming). This enzyme catalyses the following chemical reaction (2E,6E)-farnesyl diphosphate (–)-α-isocomene + diphosphate This enzyme is isolated from the roots of the plant Matricaria chamomilla var. recutita (chamomile).
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