Zeerust is a commercial town situated in Ngaka Modiri Molema district North West Province, South Africa. It lies in the , approximately 240 kilometres northwest of Johannesburg. It lies on the N4, the main road link between South Africa and Botswana. There are large cattle ranches in the area, as well as wheat, maize, tobacco and citrus fruit farms. There are also fluorite and chromite mines in the vicinity. Tourism is also a developing industry.