U.S. Route 466 (US 466) was an east–west United States highway. Though it reached a length of around 500 miles (805 km), the route was co-signed with other US routes for much of its length. When California deleted most of its U.S. Highways in the mid-1960s, including US 466 in 1964, there was no longer a need for the designation. The general route between Barstow and Kingman is now more directly served by Interstate 40. The route is known for being the highway on which actor James Dean died in a car accident on September 30, 1955, at the intersection of CA 41 near Cholame, California.