The Sisters Brothers is a 2011 Western novel by Canadian-born author Patrick deWitt. The darkly comic story takes place in Oregon and California in 1851. The narrator, Eli Sisters, and his brother Charlie are assassins tasked with killing Hermann Kermit Warm, an ingenious prospector who has been accused of stealing from the Sisters' fearsome boss, the Commodore. Eli and Charlie experience a series of misadventures while tracking down Warm which resemble the narrative form of a picaresque novel, and the chapters are, according to one review, "slightly sketched-in, dangerously close to a film treatment."