Sibylle Christine of Anhalt-Dessau (11 July 1603 in Dessau – 21 February 1686 in Hanau), was by birth a member of the House of Ascania and princess of Anhalt-Dessau. Through her two marriages she became Countess of Hanau-Münzenberg and Hanau-Lichtenberg. Sibylle Christine was the sixth daughter of John George I, Prince of Anhalt-Dessau, but third-born daughter of his second wife Dorothea, daughter of John Casimir of Simmern.