Sergio Héctor Comba (born 15 October 1978) is a retired Argentine footballer who played as a striker. He has played for several teams as Atlético Rafaela, Sarmiento, Ferro Carril Oeste, FC Nantes, Pistoiese, San Martín de Tucumán, Defensores, CA Huracán, Cruz Azul Hidalgo, Defensores, Atlético Rafaela, San Martín de Mendoza, YF Juventus, Sangiovannese, Celano, Defensores de Belgrano and Santiago Morning. He also had a brief spell in Ligue 1 with FC Nantes. In mid 2009, Comba was signed for Santiago Morning, in this club he played a total of 34 matches and also scored a total of 17 goals.