The rectal venous plexus (or hemorrhoidal plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the vaginal venous plexus in the female. A free communication between the portal and systemic venous systems is established through the rectal venous plexus. This allows administration of some medications normally given by mouth to be given rectally, while still bypassing first pass metabolism. Examples include rectal Diazepam and orally dissolving medications.