Pir Muhammad Mirza (c.1379 – 8 May 1409) was a Timurid prince and a grandson of the Central Asian conqueror Timur by his eldest son Umar Shaikh Mirza I. Unlike many of his relatives, Pir Muhammad did not assert a claim to the throne in the aftermath of Timur's death. Instead, he consolidated and maintained the position that he had previously been given by his grandfather. He was assassinated by his own soldiers while campaigning in 1409.