Mezzo Soprano (1 March 2000 – 2013) was an American-bred Thoroughbred racehorse and broodmare. After winning her only race as a juvenile in 2002 she developed into a top-class performer in the following year, winning the UAE 1000 Guineas, Galtres Stakes and Prix Vermeille. She was also placed in the Lupe Stakes, Ribblesdale Stakes and Prix de Psyché. She had some success as a broodmare.