Louise-Marie Thérèse Charlotte Isabelle of Orléans (3 April 1812 – 11 October 1850) was the first queen of the Belgians as the second wife of King Leopold I from their marriage on 9 August 1832 until her death in 1850. She was the second child and eldest daughter of the French king Louis Philippe I and his wife, Maria Amalia of the Two Sicilies. Louise rarely participated in public representation, but acted as the political adviser of her spouse. Her large correspondence is a valuable historical source of the period and has been published.