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The Karamea River is a river of New Zealand. It is located in the Tasman and West Coast Regions of the South Island. The river rises within Kahurangi National Park in the of the Southern Alps. The river rises to the east of , meandering west briefly before turning north. After some 25 kilometres it again turns west, to enter a series of small lakes where its waters are joined by those of the Roaring Lion River.