Humphrey Orme (1620 – 2 March 1671) was an English politician who sat in the House of Commons in 1654 and from 1660 to 1671. Orme was the son of Humphrey Orme of Peterborough and his wife Mary Orme, daughter of Humphrey Orme of Compton Dundon, Somerset. He was baptised on 12 October 1620. Orme's grandfather was a strong Royalist. Nevertheless, Orme supported Parliament, being in 1650 one Commissioners for raising money in Northamptonshire. In 1654, he was elected Member of Parliament for Peterborough in the First Protectorate Parliament. Orme died at the age of 50.