Humberto de la Calle Lombana (Spanish pronunciation: [umˈbeɾto ðe la ˈkaʝe lomˈbana]; born 14 July 1946 in Manzanares, Caldas) is a Colombian lawyer and politician. He served as Vice President of Colombia from 1994 to 1997. De La Calle served in the cabinet as Interior Minister under two Presidents, Andrés Pastrana and César Gaviria. He also served as Ambassador to Spain and the United Kingdom. After 2003, De La Calle worked at his own Law firm which specialises in advising and representing international clients in Colombia. In October 2012 he was appointed by President Juan Manuel Santos as the chief negotiator in the peace process with the FARC.