State Route 73 (SR 73) is a 78.1-mile-long (125.7 km) state highway in the eastern part of the U.S. state of Georgia. It connects Glennville with the South Carolina state line, via Claxton, Statesboro, Dover, and Sylvania. Except for a brief portion in the Sylvania area, it is completely concurrent with U.S. Route 301 (US 301). Its southern terminus is at US 25/US 301/SR 23/SR 57 and SR 144 in Glennville. Its northern terminus is at the South Carolina state line, east of Millhaven, where US 301 enters that state.