The former First Church of Christ, Scientist, built in 1916 in the Classical Revival style, is a historic Christian Science church edifice located at 132 E. 4th Street in Neillsville, Wisconsin. It was designed in the form of a Greek cross by Chicago architect for Christian Science Society, Neillsville, which had been organized in January, 1912 and which later became First Church of Christ, Scientist. Its front portico is supported by four large Tuscan columns. While small in size, the building projects a large presence. Its auditorium windows are of green opalescent art glass. On March 31, 2003, it was added to the National Register of Historic Places.