Edward Charlton (also Cherleton or Charleton), 5th Baron Charlton, KG (1370–1421), 5th and last Lord Charlton of Powys, was the younger son of John Charlton, the third baron, and his wife, Joan, daughter of Lord Stafford. In 1420 Charlton conferred a new charter on the Cistercian abbey of Strata Marcella, of which his house was patron. He died on 14 March 1421.