The Drake University Campus Historic District is located in Des Moines, Iowa, United States. The historic district contains six buildings. Five of the buildings are collegiate buildings on the Drake University campus and one is a church. The period of significance is from when the university was founded in 1881 to the end of the presidency of Hill M. Bell in 1918. The historic district has been listed on the National Register of Historic Places since 1988. It is part of the Drake University and Related Properties in Des Moines, Iowa, 1881—1918 MPS.