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David Middleton Greig FRSE FRCSE LLD TD (1864-4 May 1936) was a Scottish surgeon who worked for most of his career at Dundee Royal Infirmary. He developed an interest in diseases of bone and came to be regarded as an international authority on the subject. He wrote numerous papers on skeletal abnormalities and Greig cephalopolysyndactyly syndrome (first described in 1926) is named after him. Over the course of his career he amassed a large collection of skulls demonstrating various bony abnormalities. After retiring from surgical practice he became conservator of the Museum of the Royal College of Surgeons of Edinburgh at Surgeons' Hall. He donated 250 skulls to Surgeons' Hall Museum, where some remain on display as part of the Greig Collection.

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