Cassius M. Vaughn (born November 3, 1987) is a former Canadian football defensive back. He was signed by the Denver Broncos as an undrafted free agent in 2010. He played college football at Ole Miss. In the NFL, Vaughn has also played for the Indianapolis Colts, Detroit Lions Baltimore Ravens and San Diego Chargers. He made his CFL debut in 2016 with the Hamilton Tiger-Cats.