Brest Bretagne Handball is the name of a French handball club from Brest, Brittany. This team currently competes in the French Women's Handball First League from 2016 and the 2021–22 Women's EHF Champions League. In the 2020–2021 EHF Champions League, the club reached the EHF Final 4 tournament for the first time in the club's history. They won an historic semifinal, against the three-time defending champions and five-time winners from Győri Audi ETO KC. In the final, they were defeated by Norwegian Vipers Kristiansand, who also claimed their first title.