Aristobulus V of Chalcis (Greek: Ἀριστόβουλος) was a son of Herod of Chalcis and his first wife Mariamne. Herod of Chalcis, ruler of Chalcis in Iturea, was a grandson of Herod the Great through his father, Aristobulus IV. Mariamne was a granddaughter of Herod the Great through her mother, Olympias; hence Aristobulus was a great-grandson of Herod the Great on both sides of his family.