Ambassel (Amharic: ዐምባሰል) is a woreda in Amhara Region, Ethiopia, and an amba, or mountain fortress, located in the woreda. The word Ambasel is derived from two words "Amba" from the Amharic word for plateau, and “Asel” from the Arabic language, which means honey. Together, it means “plateau of honey” or the “land of honey” the woreda is named for this feature. Located in the Debub Wollo Zone, Ambassel woreda is bordered on the west by the Bashilo which separates it from Tenta, on the north by the Semien Wollo Zone, on the southeast by the Mille River which separates it from Tehuledere, and on the south by Kutaber; the Walano, a tributary of the Bashilo, defines most of its southern border. Its largest town is Wuchale.