Alessandro (HWV 21), is an opera composed by George Frideric Handel in 1726 for the Royal Academy of Music. Paolo Rolli's libretto is based on the story of Ortensio Mauro's La superbia d'Alessandro. This was the first time the famous singers Faustina Bordoni and Francesca Cuzzoni appeared together in one of Handel's operas. The original cast also included Francesco Bernardi who was known as Senesino.