The 2015–16 Creighton Bluejays men's basketball team represented Creighton University in the 2015–16 NCAA Division I men's basketball season. The Bluejays, led by sixth-year head coach Greg McDermott, played their home games at the CenturyLink Center Omaha, and were members of the Big East Conference. They finished the season 20–15, 9–9 in Big East play to finish in sixth place. They lost to Seton Hall in the quarterfinals of the Big East tournament. They received an invitation to the National Invitation Tournament where, as a #4 seed, they defeated Alabama and Wagner to advance to the quarterfinals where they lost to BYU.