The Yoshino River (吉野川 Yoshino-gawa) is a river on the island of Shikoku, Japan. It is 194 km (121 mi) long and has a watershed of 3,750 km2 (1,450 sq mi). It is the second longest river in Shikoku (slightly shorter than the Shimanto), and is the only river whose watershed spreads over the four prefectures of the island. It is regarded as one of the three greatest rivers of Japan along with the Tone and the Chikugo, and is nicknamed Shikoku Saburō (四国三郎; Saburō is a popular given name for a third son).